Respiratory, Digestive and Cardiovascular Diseases and Infections Flashcards
What is emphysema?
Excess high levels of irritating particles taken into the lungs
What is the pathophysiology of emphysema?
- irritating particles damage alveoli : they lose elasticity (epithelial tissue is replaced with fibrous tissue)
- break down of alveoli decreases surface area of lungs = less surface area for gas exchange
- loss of elasticity means that lungs are constantly inflated and breathing out requires voluntary effort
What are the symptoms of emphysema?
- coughing and wheezing (most people that have emphysema also have bronchitis - coughing clears mucous from airways)
- shortness of breath (due to effort needed to breath out - shallow breathing, and destruction of alveoli)
What are the lifestyle factors that effect emphysema?
- smoking (smoke particles break down lungs and irritate airways)
–>also causes inflammation and damages cilia causing mucous production and swollen airways - exposure to fumes or dust (damage lining of lungs and airways = break down elasticity)
What is lung cancer?
development of mass of cells, that divide uncontrollably starting in the lungs - a tumour
What is the pathophysiology of lung cancer?
- particles irritate mucous membrane causing excessive mucous production
- cells at base of mucous membrane rapidly divide and mucous build up cannot be removed = rupturing the alveoli, pleural effusion = build up of fluid between lung and chest wall
What are the symptoms of lung cancer?
- coughing or wheezing (body clearing out chemicals and mucous from airways)
- shortness of breath (pleural effusion, if cancer blocks airways)
- coughing blood (a sign of tissue destruction and inflammation in the airway)
What are the lifestyles factors of lung cancer?
- smoking (carcinogens in cigarettes change tissue in lungs)
- At first cells may be able to repair themselves but after continuous exposure they become too damages and turn into cancerous cells
What is pneumonia?
infection caused by bacteria, viruses or fungi
What is the pathophysiology of pneumonia?
-inflammation of alveoli causes it to be filled with fluid and mucous = reducing amount of air contained
- surface area of alveoli decreases = surface for gas exchange decreases
What are the symptoms of pneumonia?
- coughing and wheezing (attempt to clear mucous from air ways)
- difficulty breathing (not enough surface area for efficient gas exchange)
- fever (high body temperature in order to kill of bacteria, fungi or virus)
What are the lifestyle factors of pneumonia?
- smoking (damages body’s natural defence against infection)
- Arise due to other respiratory diseases such as asthma, COPD, cystic fibrosis
What is tuberculosis?
An infection caused by mycobacterium, top 3 infectious diseases causing death
What is the pathophysiology of tuberculosis?
- destroys epithelial tissue in lungs and other parts of body
- TB travels through the bloodstream to other parts of the body
What are the symptoms of tuberculosis?
- coughing blood (a sign of tissue damage and inflammation in airway)
- chills, fatigue, fever (fight of bacteria)
- shortness of breath (pleural effusion, build up of fluid between chest wall and lung)
What are the lifestyle factors of tuberculosis?
- close contact with an infectious person: spread by tiny droplets that are inhaled into the lungs
What is asthma?
Medical condition that causes difficulty breathing due to narrowing of airways
What is the pathophysiology of asthma?
- muscles in the bronchioles go into spasm by triggers = narrowing airways
- irritation of membranes causes excessive mucous production
What are the symptoms of asthma?
- coughing or wheezing (clear out airways of mucous)
- shortness of breath (narrow airways, reduced volume of air)
What are the lifestyle factors of asthma?
- smoking (destroys lung tissue and irritates airways, triggers spasms)
- family history
- exposure to fumes or dust (also triggers spasms)
- air pollution
What is the treatment of emphysema?
emphysema cannot be cured, but treatment can be used to relieve symptoms and slow progression of disease:
- lifestyle changes
- bronchodilators (relax constricted airways)
- inhaled steroids (reduce inflammation)
- antibiotics
- supplemental oxygen
- surgery (lung transplant, or volume reduction)
What is the treatment of lung cancer?
Depending on type of lung cancer and how far it has spread:
- surgery (to remove cancerous cells)
- radiotherapy (radioactive waves to kill cells)
- chemotherapy (medicine to shrink and kill cells)
- targeted therapy (drugs to block growth and spread)