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Respiratory Week 1 > Respiratory antibiotic classes and mechanisms > Flashcards

Respiratory antibiotic classes and mechanisms Flashcards

1
Q

name the two folate synthesis inhibitors

A

sulfamethoxazole

trimethoprim

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2
Q

name the four fluoroquinolones

A

gemfloxacin
ciprofloxacin
levofloaxacin
moxifloxacin

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3
Q

name the three broad sprectrum b lactams

A

amoxicillin
ampicillin
piperacillin

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4
Q

name the B lactam monobactam

A

aztreonam

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5
Q

name the carabpenem B lactams

A

imipenem

meropenem

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6
Q

name the cephalosporin B lactams

A 
cefuroxime
ceftriaxone
cefotaxime
cefpodoxime
ceftazidime
cefepime
ceftaroline
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7
Q

name the glycopepide drug

A

vancomycin

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8
Q

name the three aminoglycosides

A

gentamicin
tobramycin
amikacin

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9
Q

name the tetracycline

A

doxycycline

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10
Q

name the three macrolides

A

azithromycin
erythromycin
clarithromycin

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11
Q

what is the mechanism of ciprofloxacin levofloxacin moxifloxacin and gemifloxacin

A

DNA damaging drugs

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12
Q

what is the mechaism of B lactams (including penicillins, monobactams, carbapenems, cephalosporins)

A

cell wall synthesis inhibition

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13
Q

what is the mechanism of vancomycin?

A

cell wall synthesis inhibition

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14
Q

whats is the mechanism of gentamicin, tobramycin and amikacin?

A

protein inhibition via 30s subunit

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15
Q

what is the mechanism of doxycycline?

A

protein inhibition via 30s subunit

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16
Q

what is the mechanism of erythromycin, clarithromycin, azithromycin?

A

protein inhibition via 50s subunit

17
Q

what is the mechanism of linezolid?

A

protein inhibition via 50s subunit

18
Q

what is the mechanism of clindamycin?

A

protein inhibition via 50s subunit

19
Q

do sulfamethoxazole/trimethoprim target gram neg/pos/both?

A

BOTH

20
Q

do fluroquinolones target gram neg/pos/both?

A

BOTH

21
Q

do broad spectrum B lactams target gram neg/pos/both?

A

BOTH

22
Q

does aztreonam target gram neg/pos/both?

A

negative

23
Q

do carbapenems target gram neg/pos/both?

A

BOTH

24
Q

what is the one cephalosporin that only targets gram negative?

A

ceftazidime

25
Q

does vancomycin target gram neg/pos/both?

A

positive

26
Q

do aminoglycosides target gram neg/pos/both?

A

gram negative

27
Q

does doxycycline target gram neg/pos/both?

A

BOTH

28
Q

do macrolides target gram neg/pos/both?

A

BOTH

29
Q

does linezolid target gram neg/pos/both?

A

gram positive

30
Q

does clindamycin target gram neg/pos/both?

A

BOTH

31
Q

does colistin target gram neg/pos/both?

A

negative

Respiratory Week 1 (18 decks)

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