Respiratory antibiotic classes and mechanisms Flashcards
name the two folate synthesis inhibitors
sulfamethoxazole
trimethoprim
name the four fluoroquinolones
gemfloxacin
ciprofloxacin
levofloaxacin
moxifloxacin
name the three broad sprectrum b lactams
amoxicillin
ampicillin
piperacillin
name the B lactam monobactam
aztreonam
name the carabpenem B lactams
imipenem
meropenem
name the cephalosporin B lactams
cefuroxime ceftriaxone cefotaxime cefpodoxime ceftazidime cefepime ceftaroline
name the glycopepide drug
vancomycin
name the three aminoglycosides
gentamicin
tobramycin
amikacin
name the tetracycline
doxycycline
name the three macrolides
azithromycin
erythromycin
clarithromycin
what is the mechanism of ciprofloxacin levofloxacin moxifloxacin and gemifloxacin
DNA damaging drugs
what is the mechaism of B lactams (including penicillins, monobactams, carbapenems, cephalosporins)
cell wall synthesis inhibition
what is the mechanism of vancomycin?
cell wall synthesis inhibition
whats is the mechanism of gentamicin, tobramycin and amikacin?
protein inhibition via 30s subunit
what is the mechanism of doxycycline?
protein inhibition via 30s subunit
what is the mechanism of erythromycin, clarithromycin, azithromycin?
protein inhibition via 50s subunit
what is the mechanism of linezolid?
protein inhibition via 50s subunit
what is the mechanism of clindamycin?
protein inhibition via 50s subunit
do sulfamethoxazole/trimethoprim target gram neg/pos/both?
BOTH
do fluroquinolones target gram neg/pos/both?
BOTH
do broad spectrum B lactams target gram neg/pos/both?
BOTH
does aztreonam target gram neg/pos/both?
negative
do carbapenems target gram neg/pos/both?
BOTH
what is the one cephalosporin that only targets gram negative?
ceftazidime
does vancomycin target gram neg/pos/both?
positive
do aminoglycosides target gram neg/pos/both?
gram negative
does doxycycline target gram neg/pos/both?
BOTH
do macrolides target gram neg/pos/both?
BOTH
does linezolid target gram neg/pos/both?
gram positive
does clindamycin target gram neg/pos/both?
BOTH
does colistin target gram neg/pos/both?
negative
