Intracellular Bacteria Flashcards
is chlamydia facultative, obligate intracellular or obligate extracellular?
obligate intracellular
describe how chlamydia replicates? what are the two stages?
elementary bodies are outside of cells and inactive and look for cells to enter into…once in cell becomes reticulate body that can replicate and then eventually burst out and is elementary body again
is legionella facultative, obligate intracellular or obligate extracellular?
facultative
is legionella pneumophila gram neg or pos?
gram negative
how is legionella spread?
inhalation of contaminated water…not person to person
what is the name of another type of disease from legionella that is not pneumonia?
pontiac fever
describe how pontiac fever presents
it is more flu ike with fever headache diarrhea and fatigue…lasts a week no treatment
what cell does legionella infect?
macrophages…specifically the lysosomes
what is the immune response to legionella?
Th1 mediated response with IFN-gamma…just like myco TB
what drug to treat legionella?
macrolides (azithromycin)
is chlamydia gram neg or pos?
gram negative
what is the classic pneumonia that chlamydia causes?
walking pneumonia
how is chlamydia pneumoniae transmitted?
person to person easily
what drug to treat chlamydia?
doxycycline
what other pneuomonia infection is chlamydia hard to distinguish from?
mycoplasma
what type of agar does legionella grow on?
charcoal yeast agar..takes 3-5 days
what are cold agglutinins?
antibodies that agglutinate at 4C and not at 37C
which two pneumonia causing organisms are commonly tested for cold agglutinins? which is positive and which is negative?
Mycoplasma is positive
Legionella is negative
what cells does chlamydia affect?
macrophages and epithelial cells
what is chlamydia psittaci and what animal is it related to?
it is another strand of chlamydia that is related to birds….like parrots
what type of agar do you grow Myco TB on?
Lowenstein Jensen agar
