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Respiratory Week 1 > Intracellular Bacteria > Flashcards

Intracellular Bacteria Flashcards

1
Q

is chlamydia facultative, obligate intracellular or obligate extracellular?

A

obligate intracellular

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2
Q

describe how chlamydia replicates? what are the two stages?

A

elementary bodies are outside of cells and inactive and look for cells to enter into…once in cell becomes reticulate body that can replicate and then eventually burst out and is elementary body again

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3
Q

is legionella facultative, obligate intracellular or obligate extracellular?

A

facultative

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4
Q

is legionella pneumophila gram neg or pos?

A

gram negative

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5
Q

how is legionella spread?

A

inhalation of contaminated water…not person to person

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6
Q

what is the name of another type of disease from legionella that is not pneumonia?

A

pontiac fever

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7
Q

describe how pontiac fever presents

A

it is more flu ike with fever headache diarrhea and fatigue…lasts a week no treatment

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8
Q

what cell does legionella infect?

A

macrophages…specifically the lysosomes

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9
Q

what is the immune response to legionella?

A

Th1 mediated response with IFN-gamma…just like myco TB

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10
Q

what drug to treat legionella?

A

macrolides (azithromycin)

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11
Q

is chlamydia gram neg or pos?

A

gram negative

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12
Q

what is the classic pneumonia that chlamydia causes?

A

walking pneumonia

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13
Q

how is chlamydia pneumoniae transmitted?

A

person to person easily

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14
Q

what drug to treat chlamydia?

A

doxycycline

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15
Q

what other pneuomonia infection is chlamydia hard to distinguish from?

A

mycoplasma

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16
Q

what type of agar does legionella grow on?

A

charcoal yeast agar..takes 3-5 days

17
Q

what are cold agglutinins?

A

antibodies that agglutinate at 4C and not at 37C

18
Q

which two pneumonia causing organisms are commonly tested for cold agglutinins? which is positive and which is negative?

A

Mycoplasma is positive

Legionella is negative

19
Q

what cells does chlamydia affect?

A

macrophages and epithelial cells

20
Q

what is chlamydia psittaci and what animal is it related to?

A

it is another strand of chlamydia that is related to birds….like parrots

21
Q

what type of agar do you grow Myco TB on?

A

Lowenstein Jensen agar

Respiratory Week 1 (18 decks)

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