Respiration and Breathing 2 Flashcards

1
Q

What does blood flow through lungs allow

A

Transfer of gases to and from the respiring tissues of the body

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2
Q

What do gases move according to

A

They move down a concentration gradient

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3
Q

How is pulmonary circulation specialised

A

Gas composition of blood in pulmonary arteries and veins opposite to those in systemic circulation. Pressures in pulmonary circulation are very low. Pulmonary artery walls are thin and contain little smooth muscle. Pulmonary vascular resistance is low.

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4
Q

How do you work out vascular resistance

A

(input pressure - output pressure)/ blood flow

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5
Q

How do you work out alveolar ventilation rate

A

(tidal volume- dead space) x respiratory rate

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6
Q

What is alveolar rate

A

4 litres per minute

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7
Q

What is dead space

A

150ml

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8
Q

What is tidal volume

A

1/2L

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9
Q

What is respiratory rate

A

11/min when sitting

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10
Q

What is blood gas composition regulated by

A

Changes in alveolar ventilation rate

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11
Q

What is hypoventilation

A

When ventilation is reduced and is not meeting demands. There is not enough O2 and increased conc of CO2 as it id not removed

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12
Q

What is hyperventilation

A

Ventilation is increased above demands. Too deep/ rapid breathing. Oxygen conc increases but is limited by saturation levels. Decrease in conc of CO2

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13
Q

Why is hyperventilation dangerous

A

Decrease in conc of CO2 which increases pH making blood more alkaline

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14
Q

What sets the basic rhythm and pattern of breathing

A

The brainstem

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15
Q

How can ventilation be modified

A

Feedback from higher brain centres (cortex, hypothalamus, limbic system). Feedback from receptors in the lung (stretch, irritants). Feedback from peripheral and central chemoreceptors

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16
Q

What does an increase in the arterial partial pressure of CO2 result in

A

An increase in minute ventilation rate

17
Q

What are sensitive to changes in blood chemistry

A

Chemoreceptors

18
Q

What are the 2 types of chemorecptors

A

Peripheral and central

19
Q

Describe peripheral receptors

A

Acutely sensitive to changes in arterial pressure of CO2. Small increase in PCO2 causes an immediate increase in minute ventilation

20
Q

Describe central receptors

A

Sensitive to longer-term changes in PCO2

21
Q

Which receptors are sensitive to changes in arterial PO2

A

Peripheral chemoreceptors

22
Q

What do peripheral chemoreceptors do if arterial PO2 drops

A

If arterial PO2 drops below 60mmHg minute ventilation rises

23
Q

When are ventilatory responses more sensitve

A

During hypercapnia and hypoxia

24
Q

What is hypercapnia

A

When PCO2 is elevated

25
Q

What is hypoxia

A

When PO2 is reduced