Reproductive Pharmacology

Question 1

How are anabolic steroids distributed?

Answer 1

1. Oral
2. oil-based injection
3. water-based injection

Question 2

What are ADRs of anabolic steroids

Answer 2

1. Water retention
2. Testicular atrophy
3. Insomnia
4. Loss of libido
5. Nose bleeds
6. CHF
7. Psychological effects
8. Increased LDL
9. Liver damage
10. Gynecomastia

Question 3

Aging, smoking, hypertension, diabetes, hyperlipidemia, arterial disease, psychological factors, and drugs are all contributing factors to….

Answer 3

Erectile dysfucntions

Question 4

What are some drugs that cause erectile dysfunction?

Answer 4

1. Antihypertensive drugs
2. CNS depressants
3. Psychotropic agents
4. Other drugs (chemotherapy, histamine 2 blockers, levodopa)

Question 5

What are drugs used to treat erectile dysfunction?

Answer 5

Phosphodiesterase type 5 inhibitors (end in AFIL, shelf name = viagra, levitra, cialis)

Question 6

What are ADRs of phosphodiesterase type 5 inhibitors?

Answer 6

1. Headache, flushing and nasal stuffiness
2. Visual disturbances
3. Enhanced effect of nitrates on blood pressure -hypotension

Question 7

What are the ADR of contraceptive agents?

Answer 7

In general, clotting disorders and events that occur from them

Question 8

What cancers do contraceptives increase the risk for?

Answer 8

1. Breast
2. Cervical
3. Liver
   (Evidence for decreased risk Ovarian and Endometrial cancer)

Question 9

What drugs are used to reduce symptoms of postmenopausal women related to decreasing estrogen levels?

Answer 9

Hormone replacement therapy

Question 10

What are the benefits of hormone replacement therapy?

Answer 10

1. Reduce osteoporosis

2. colorectal cancers

Question 11

What are the risks of estrogen therapy?

Answer 11

1. Stroke
2. Venous thromboembolism
3. Gallbladder disease
4. Breast Cancer