Pharmacodynamics and Pharmacokinetics Flashcards
Study of how the body deals with drugs
Pharmacokinetics
Entrance of drugs anywhere in the GI tract from the mouth to the rectum
Enteral
Entrance of drugs by injection, inhalations, application to the skin, etc.
Parenteral
Specialized parenteral; apply to skin but goal is to go through the skin and into the body
Transdermal
In the Enteral route, this happens when the liver metabolizes the drugs that come in and potentially metabolizes drugs before they get to the targeted organ
First Pass effect
Drug administered by putting it in the cheek
Buccal
Drug administered by putting it under the tongue
Sublingual
Are oil-based or water-based intramuscular injections more quickly distributed?
Water-based
Injection into spinal subarachnoid space
Intrathecal
Are lipid-based or water-based drugs more common in topical administration?
Lipid-based; can work their way through the skin to diffuse into the body
Ultrasound is used to drive drugs down through the skin
Phonophoresis
Transdermal administration of a drug you want to act below the skin
Transdermal patches
In general, do lipid-solvable or water-soluble drugs work faster?
Lipid-Solvable; think bi-lipid layer of cells