Intro to Pharmacology Flashcards
What are the two things PTs are looking for for in regards to pharmacology?
- Drug’s effect on the body
2. The body’s response to the drug
How many phases of human studies are there in developing/approving therapeutic agents?
3
This phase looks for what happens when the drug gets administered, obvious side effects and uses a small group of healthy people?
Phase I
This phase uses a small group of people who have the condition that the drug is attempting to treat; looks at drug levels, how it gets metabolized, adverse effects, safety
Phase II
This phase uses a large group of people who have the condition that the drug is attempting to treat; looks at drug levels, how it gets metabolized, adverse effects, safety
Phase III
Drug is for people with serious illnesses, so it may move through approval stages faster
Fast track
When drug is used to treat something it’s not intended for
off-market
Name some potential problems with OTC medications
- Prices may be lower, but cost to pt may be higher
- Emphasis on self-care (some may misdiagnose)
- Lack of recognition by consumer that these are real drugs with potential adverse effects, interxns w/ prescriptions, may delay use of more effective prescription drugs
Controlled substance: highest potential for abuse, no recognized medical benefits
Schedule I
Controlled substance: high potential for abuse, but some medical benefits
Schedule II
Controlled substance: Lower abuse potential, mild to moderate physical dependence
Schedule III
Controlled substance: Potential abuse
Schedule IV
Controlled substance: No potential for abuse
Schedule V
Categories of drugs
Drug class
Tells what a drug is used for
Indication
If a condition exists, you DO NOT want to take that drug
Contraindication
If condition exists, you may not want to take that drug; Pt may be at higher risk, but there may be reasons you want that person to take a drug
Caution
Bad things that happen to people who receive a drug
Adverse effects
Happens when drugs combine with other things in the body; drugs can magnify/inhibit each other; may have effects due to diet
Interactions
What are the PT’s responsibilities when it comes to a patient’s medication?
- Medication administration
- Assessment of medication’s effects
- Intervention to increase tolerance of medication regimen
- Providing patient reaching about medications and the medication regimen
Measures the effect of the drug on the body
Biophysiological labs
Utilization of drugs to prevent, treat, or diagnose disease
Pharmacotherapeutics
How the body deals with the drug with respect to absorption, distribution, and elimination
Pharmokinetics
What effects the drug as on the body including the mechanism in which it exerts its effects
Pharmacodynamics