reproductive endocrinology part II Flashcards
how long is the fertilisation window after ovulation
24 hours
How does implantation of fertilized cells into the uterus occur?
After fertilization, the zygote develops into a blastocyst, which attaches to the uterine wall (endometrium). The trophoblast cells invade the endometrium, securing the embryo and forming the basis of the placenta.
How does the placenta develop at the onset of pregnancy?
The placenta forms from the trophoblast and maternal tissue. It facilitates nutrient, gas, and waste exchange between mother and fetus and produces hormones like hCG, progesterone, and estrogen to maintain pregnancy.
what is detected in the blood or urine to confirm pregnancy
human chorionic gonadotropin (hCG)
what is the role of human chorionic gonadtropin in early pregnancy
maintains the corpus luteum
what can be injected to help people get pregnant
hCG
what spikes at the start of pregnancy to prevent the destruction of corpus luteum
hCG
role of progesterone in pregnancy
Maintains uterine lining and prevents uterine contractions.
role of oestrogen in pregnancy
Promote uterine growth (myometrium) and blood flow.
role of hPL (human placental lactogen) in pregnancy
Prepares breasts for lactation and regulates maternal metabolism.
Which hormones are involved in maintaining gestation and how?
Progesterone: Prevents uterine contractions.
Relaxin: Softens the cervix and relaxes pelvic ligaments.
Estrogen: Supports uterine growth and prepares for labor.
What are the major events during parturition?
Key Hormones: Oxytocin (induces contractions) and prostaglandins (soften the cervix).
role of prostaglandins during pregnancy
help dilate your cervix (make it wider) and cause uterine contractions.
How does lactation begin?
Prolactin, stimulated by reduced progesterone and estrogen after birth, promotes milk production. Oxytocin triggers milk ejection (let-down reflex) during suckling.
How does the suckling response work?
Suckling stimulus: Increases prolactin (milk production) and oxytocin (milk ejection).
Inhibition of ovulation: Suppresses FSH and LH via prolactin, delaying the menstrual cycle.