physiological homeostasis Flashcards

1
Q

define homeostasis

A

maintenance of a constant internal environment

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2
Q

describe the principles of and components of physiological feedback loop

A

sensor detects change in physiological condition
comparator processes info and determines response
effector carries out necessary action to restore balance

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3
Q

identify factors under homeostatic control

A

nutrients
gases
waste products
pH
salt and electrolytes
temperature
volume and pressure

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4
Q

describe immediate compensatory regulatory responses

A

occurs within seconds or minutes
autonomic nervous system

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5
Q

give an example of immediate compensatory regulatory responses

A

baroreceptor reflex
shivering

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6
Q

describe short term compensatory regulatory responses

A

occurs within minutes to hours
hormonal regulation via endocrine system

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7
Q

give an example of short term compensatory regulatory responses

A

release of cortisol or adrenaline during stress
adjusting ADH during dehydration

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8
Q

describe long term compensatory regulatory responses

A

structural or functional changes to organs/tissues

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9
Q

give an example of long term compensatory regulatory responses

A

increased red blood cells at high altitude

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9
Q

what is a positive feedback loop?

A

amplifies a change in physiological response

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10
Q

give an example of a positive feedback loop

A

childbirth
contractions trigger release of oxytocin
oxytocin enhances strength contractions
contractions intensifies until baby is delivered

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11
Q

what is a negative feedback loop?

A

reverses change in physiological system to maintain homeostasis
restoring back to set point

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12
Q

give an example of negative feedback loop

A

body temp regulation
when body temp rises the brain signals sweat glands to produce sweat
sweat cools the body to reduce body temp back to normal

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13
Q

what is feedforward

A

anticipatory change

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14
Q

Give an example of feedforward

A

muscle memory

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15
Q

explain a situation where there is a modification of set points (COPD)

A

persistent hypoxaemia causes the body to adapt to a level of hypocapnia

16
Q

explain a situation where there is a modification of set points (pyrexia)

A

COX-2 generates PGE2 which triggers fever via TLR