adrenal gland hormones Flashcards

1
Q

what is aldosterone’s class and site of synthesis

A

mineralcorticoid
zona glomerulosa of adrenal cortex

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2
Q

what is noradrenaline class and site of synthesis

A

catecholamine
adrenal medulla

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3
Q

what is adrenaline class and site of synthesis

A

catecholamine
adrenal medulla

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4
Q

what triggers RAAS

A

decrease in blood pressure or Na cause renin release

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5
Q

where is angiotensiogen produced

A

liver

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6
Q

what converts angiotensin I to angiotensin II

A

ACE

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7
Q

when aldosterone is released what effect does it have

A

increases Na reabsorption and K excretion to increase blood pressure

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8
Q

elevated ________ levels in blood also can stimulate aldosterone secretion

A

potassium

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9
Q

which pituitary hormone can stimulate aldosterone

A

ACTH

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10
Q

aldosterone location of action

A

DCT and collecting ducts

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11
Q

what type of receptors do aldosterone bind to

A

mineralcortiocoid receptors

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12
Q

what type of genes do aldosterone promote transcription of

A

Na/K ATPase pump and ENaC

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13
Q

Which adrenoceptor subtype is primarily responsible for vasoconstriction in smooth muscles?

A

a1

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14
Q

Which adrenoceptor subtype is primarily responsible for inhibiting norepinephrine release?

A

a2

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15
Q

Which adrenoceptor subtype is primarily responsible for increasing heart rate and contractility?

A

B1

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16
Q

Which adrenoceptor subtype is primarily responsible for bronchodilation and vasodilation?

A

B2

17
Q

Which adrenoceptor subtype is primarily responsible for lipolysis?

A

B3

18
Q

which adreonceptors do noradrenaline have a strong affinity for

A

a1 a2

19
Q

which adreonceptors do adrenaline have a strong affinity for

A

B1 B2 B3

20
Q

what are the consequences for excessive exposure to norepinephrine and epinephrine

A

hypertension
tachycardia
hyperglycemias