HPA- hypothalamic pituitary axis Flashcards

1
Q

adenohypophysis is related to which pituitary

A

anterior

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2
Q

neurohypophysis is related to which pituitary

A

posterior

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3
Q

How is the anterior pituitary connected to the hypothalamus?

A

hypophyseal portal system

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4
Q

What hormones are released by the anterior pituitary?

A

thyrotropin RH
gonadotropin RH
corticotropin RH
growth hormone RH
somatostatin
dopamine

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5
Q

What hormones are released by the posterior pituitary?

A

ADH
oxytocin

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6
Q

What is the primary blood supply for the anterior pituitary?

A

superior hypophyseal artery

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7
Q

Does the posterior pituitary have direct neuronal innervation?

A

yes

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8
Q

Which artery supplies the posterior pituitary?

A

inferior hypophyseal artery

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9
Q

What are the main cell types found in the anterior pituitary?

A

basophils
acidophils
chromaphobes

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10
Q

What type of hormones does the anterior pituitary secrete?

A

Growth hormone (GH)
Thyroid-stimulating hormone (TSH)
Adrenocorticotropic hormone (ACTH)
Follicle-stimulating hormone (FSH)
Luteinizing hormone (LH)
Prolactin

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11
Q

Which pituitary lobe is responsible for secreting hormones directly into the bloodstream after neuronal stimulation?

A

posterior pituitary

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12
Q

hat is the target tissue and function of Growth Hormone (GH)?

A

all tissues
Stimulates growth and development in tissues

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13
Q

What is the target tissue and function of Thyroid-Stimulating Hormone (TSH)?

A

thyroid
Stimulates the thyroid gland to produce and release thyroid hormones (T3 and T4), which regulate metabolism, energy production, and growth.

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14
Q

What is the target tissue and function of Adrenocorticotropic Hormone (ACTH)?

A

adrenal cortex
Stimulates the adrenal cortex to produce and release corticosteroids, especially cortisol

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15
Q

What is the target tissue and function of Follicle-Stimulating Hormone (FSH)?

A

ovaries and testes
Stimulates spermatogenesis and ovarian follicle production

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16
Q

What is the target tissue and function of Luteinizing Hormone (LH)?

A

ovaries and testes
In females: Triggers ovulation and promotes the formation of the corpus luteum, which secretes progesterone.
In males: Stimulates the production of testosterone by the Leydig cells in the testes.

17
Q

What is the target tissue and function of Prolactin (PRL)?

A

mammary glands
stimulates milk production

18
Q

Which anterior pituitary hormone is responsible for regulating the body’s stress response?

A

ACTH

19
Q

Which anterior pituitary hormone is involved in lactation?

A

prolactin

20
Q

What are the two key hormones released by the posterior pituitary?

A

ADH
oxytocin

21
Q

What is the target tissue and function of Oxytocin?

A

mammary glands and uterus
uterine contractions and milk ejection

22
Q

What is the target tissue and function of Vasopressin (ADH)?

A

kidneys and blood vessels
increases water reabsorption and regulates blood pressure

23
Q

What triggers the release of Vasopressin (ADH)?

A

dehydration
increase blood osmolality
low blood pressure

24
Q

What does Growth Hormone (GH) stimulate the liver to produce, and what is its role?

A

GH stimulates the liver to produce Insulin-like Growth Factor 1 (IGF-1), which promotes bone growth and tissue development by stimulating cell proliferation and inhibiting cell death (apoptosis).