Reproductive Doses

Question 1

Tamoxifene (soltamox)

Answer 1

10mg, 20mg PO, QD

Question 2

Raloxifene (evista)

Answer 2

60mg, PO, QD

Question 3

Clomiphene

Answer 3

Starting: 50mg, PO x 5 days
Dose adju: increase to 100mg, PO x 5 days

Max: 100mg, PO, QD for 5 days (up to 6 cycles)

Question 4

when should you discontinue clomiphene

Answer 4

if ovulation doesn’t occurr after 3 course of treatment (or pregnancy)

Question 5

Mestranol

Norethindrone and Mestranol combo

Answer 5

Norethindrone 1mg + Mestranol 0.05mg

Question 6

Ethinyl Estradiol

Answer 6

0.005-0.02mg/day

Question 7

Anastrozole (Arimidex)

Answer 7

1mg, PO, QD until tumor progression

Question 8

Letrozole (Femara)

Answer 8

2.5mg, PO, QD until tumor progression

Question 9

Exemstane (aromasin)

Answer 9

25mg, PO, QD until tumor progression

Question 10

Danzol for endometriosis

Answer 10

Mild: 200-400mg/day over 2 doses
Moderate/infertility: 800mg/day over 2 doses

Question 11

Mifepristone for termination of pregnancy

Answer 11

1. 200mg PO x 1 dose
2. 800 mcg buccally, 1-2 days after 1st dose (2 200mcg tab in each cheek)
3. evaluate @ 7-14 days, admin another 800mcg bucally if needed

Question 12

Ulipristal (ella)

Answer 12

30mg, PO, within 120 hrs of unprotected intercourse

Question 13

Rhogam

Answer 13

300 ug (1500 IU) IV/IM
if fetal blood >30ml, admin 300ug for every 30ml

Question 14

Oxytocin (pitocin) initial dose

Answer 14

0.5-1miliunits/min
gradually increase in 1-2 miliunits/min over 30-60minutes until desired contraction pattern is obtained

Question 15

Oxytocin (pitocin) post delivery administration

Answer 15

10 units after delivery of the placenta for post partum bleeding