Pharm Cardio Redemption Flashcards
what can amiodarone do to EKG segments?
elongate QT interval
what vitamin is used as a cholesterol lowering medication?
Nicotinic acid
a patient has an extreme cardiovascular disease and a perisistent arrhythmia. what drug caused it?
quinidine
what drug can cause a lupus-erythemas type rash
hydralazine
what is the dose of lisinopril
2.5-40mg
what is the dose of HCTZ
12.5-50 mg
what drug causes pulmonary fibrosis
amiodarone
a women comes in for a pap smear and says she wants to get pregrant. what medication does she need to get off of?
ACE inhibitor
a resident tells you that amiodarone is a class 3 drug, what is the MOA
it interferes with outward K+ channels
what drug is good for renal failure and treatment of htn
loop diuretics
what beta blocker has partial agonist activity
acebutolol
what is the dosage of atropine for a-fib
100-200mg
what is the dosage of atenolol
50mg
what is the dosage of aliskiren
150mg
what is the dosage of hydralazine?
10-100mg, max of 300mg
what is the lowest bioavailability route of administration
inhalation
MOA of a statin?
HMG-CoA reductase
what drug causes reflex tachycardi?
CCB?
what medication can cause gallstones?
fibrates (gemfibrozil)
bile acid resins (cholestyramine)
what does alisriskerin bind to?
Renin
Pt had an MI and currently has V-tach, what do you give him?
lidocaine
MOA of niacin
Inhibits lipolysis and fatty acid release in adipose tissue through blockade of hormone-sensitve lipase and decreases hepatic VLDL synthesis
Nitroprusside side effect
cyanide poisoning
diuretic that acts on the distal portion of the tubule
thiazide or aldosterone inhibitors
MOA of cholesterol absorption inhibitors (ezetimibe/zetia) or Zetia+simvastatin
selective inhibition of cholesterol reabsorption at the brush border of enterocytes
-decrease LDL
-decrease slightly triglycerides
-slight increase of HDL
MOA of nitroglycerin
activate guanylyl cyclase
starting on a beta blocker, what is the regime
start on a low dose and gradually increase
effect of beta blockers in angina
reduces cardiac oxygen demand
person has hyperthyroidism and HTN, what drug does she get
Propranolol (beta blocker)
what is efficacy
how well a drug produces a response
Beta blockers with additional alpha blocking
labetalol
carrvedilol
bucindolol
what is the MOA of beta blockers
decrease cardiac output
MOA of digoxin
slow the conduction of the AV node
what is true of ezetimibe/simvastatin
use when insufficient LDL cholesterol lowering with statin alone (combo lowers LDL better than statin alone)