Pharm Cardio Redemption Flashcards

1
Q

what can amiodarone do to EKG segments?

A

elongate QT interval

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2
Q

what vitamin is used as a cholesterol lowering medication?

A

Nicotinic acid

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3
Q

a patient has an extreme cardiovascular disease and a perisistent arrhythmia. what drug caused it?

A

quinidine

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4
Q

what drug can cause a lupus-erythemas type rash

A

hydralazine

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5
Q

what is the dose of lisinopril

A

2.5-40mg

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6
Q

what is the dose of HCTZ

A

12.5-50 mg

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7
Q

what drug causes pulmonary fibrosis

A

amiodarone

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8
Q

a women comes in for a pap smear and says she wants to get pregrant. what medication does she need to get off of?

A

ACE inhibitor

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9
Q

a resident tells you that amiodarone is a class 3 drug, what is the MOA

A

it interferes with outward K+ channels

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10
Q

what drug is good for renal failure and treatment of htn

A

loop diuretics

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11
Q

what beta blocker has partial agonist activity

A

acebutolol

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12
Q

what is the dosage of atropine for a-fib

A

100-200mg

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13
Q

what is the dosage of atenolol

A

50mg

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14
Q

what is the dosage of aliskiren

A

150mg

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15
Q

what is the dosage of hydralazine?

A

10-100mg, max of 300mg

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16
Q

what is the lowest bioavailability route of administration

A

inhalation

17
Q

MOA of a statin?

A

HMG-CoA reductase

18
Q

what drug causes reflex tachycardi?

19
Q

what medication can cause gallstones?

A

fibrates (gemfibrozil)
bile acid resins (cholestyramine)

20
Q

what does alisriskerin bind to?

21
Q

Pt had an MI and currently has V-tach, what do you give him?

22
Q

MOA of niacin

A

Inhibits lipolysis and fatty acid release in adipose tissue through blockade of hormone-sensitve lipase and decreases hepatic VLDL synthesis

23
Q

Nitroprusside side effect

A

cyanide poisoning

24
Q

diuretic that acts on the distal portion of the tubule

A

thiazide or aldosterone inhibitors

25
MOA of cholesterol absorption inhibitors (ezetimibe/zetia) or Zetia+simvastatin
selective inhibition of cholesterol reabsorption at the brush border of enterocytes -decrease LDL -decrease slightly triglycerides -slight increase of HDL
26
MOA of nitroglycerin
activate guanylyl cyclase
27
starting on a beta blocker, what is the regime
start on a low dose and gradually increase
28
effect of beta blockers in angina
reduces cardiac oxygen demand
29
person has hyperthyroidism and HTN, what drug does she get
Propranolol (beta blocker)
30
what is efficacy
how well a drug produces a response
31
Beta blockers with additional alpha blocking
labetalol carrvedilol bucindolol
32
what is the MOA of beta blockers
decrease cardiac output
33
MOA of digoxin
slow the conduction of the AV node
34
what is true of ezetimibe/simvastatin
use when insufficient LDL cholesterol lowering with statin alone (combo lowers LDL better than statin alone)