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REPRO Flashcards

1
Q

Labor Induction

A

Dinoprostone

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2
Q

Infertility (Male vs Female)

A
  • Male: Leuprolide (when used in PULSATILE manner = GnRH analog / agonist)
  • Female: Clomiphene
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3
Q

Abortion Induction (4)

A
  • (-prost-)*
  • Misoprostil (PGE1): Abortion due to vasoconstriction
  • Dinoprostone (PGE2)
  • Carboprost (PGF2)
  • MTX
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4
Q

Male-Pattern Baldness

A

Finasteride (problem in male-pattern baldness = too much DHT)

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5
Q

BPH (2)

A
  • Tamsulosin (α1 antagonist selective for α1A,D receptors on prostate)
  • Finasteride (5a-Reductase Inhibitor)
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6
Q

Ectopic Pregnancy

A

MTX

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7
Q

Acne + Hirsutism in PCOS (2)

A
  • Spironolactone

- Ketoconazole

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8
Q

PCOS women who want to get pregnant

A

Clomiphene

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9
Q

Breast Cancer in postmenopausal women

A

Anastrozole / Exemestane

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10
Q

Endometriosis

A

Danazol

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10
Q

Lobular Carcinoma In-Situ Malignant Breast Tumor

A

Tamoxifen

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11
Q

Breast + Ovarian Cancer (3)

A
  • Paclitaxel (and other Taxols)
  • (-platin)
  • (-poside)
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12
Q

Ovarian Cancer

A

Topotecan

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13
Q

Prostate Cancer (2)

A
  • Leuprolide (when used in CONTIN manner = GnRH antagonist)

- Flutamide

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14
Q

Testicular Cancer

A

Bleomycin

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15
Q

Syphilis

A

Penicillin G

16
Q

Leuprolide

Mech (2 OPPOSITE, depending on use), Uses (4)?

A

MECH:

  • GnRH AGONIST (THINK: Leu used “in lie”): when used pulsatile
  • GnRH ANTAGONIST (downreg GnRH receptor in Pit): when used continuous

USES:

  • Infertility (pulsatile)
  • Precocious Puberty
  • Uterine Fibroids
  • Prostate Cancer (+ Flutamide)
17
Q

Finasteride (2)

A
  • Male-Pattern Baldness

- BPH

18
Q

Clomiphene

Mech (4 steps), Use?

A

MECH:
ANTAG at Estrogen receptors in Hypothalamus.
(Downreg receptors -> Prevents normal feedback inhib ->
↑FSH + LH release -> Stim Ovulation)

USES:
- Infertility due to Anovulation

19
Q

Tamoxifen

Mech (2 OPPOSITE, incl 2 sites in 1st category), Use?

A

MECH:

  • AGONIST at Uterus + Bone
  • ANTAGONIST on Breast tis

USES:
- ER+ Breast Cancer (rx + prev)

20
Q

Raloxifene

Mech (2 OPPOSITE), Use?

A

MECH:

  • AGONIST at Bone (↓bone resorption)
  • ANTAGONIST at Uterus

USES:
- Osteoporosis

21
Q

Hormone Replacement Therapy (HRT)

Uses (2)?

A

USES:

  • Menopausal symptoms (rx or prev)
  • Osteoporosis
22
Q

Anastrozole / Exemestane

Mech, Use?

A

MECH: Aromatase inhibitors

USES:
- Breast Cancer in postmenopausal women

23
Q

MTX (2)

A
  • Abortion

- Ectopic Pregnancy

24
Q

Danazol

Mech, Uses (2)?

A

Synthetic Androgen that acts as PARTIAL AGONIST at androgen receptors.

USES:

  • Endometriosis
  • Hereditary Angioedema

Drug Uses (18 decks)

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