ONC Flashcards
1
Q
Cancer Drugs ~GENERAL~
Mech (most)?
A
MECH: ** Folate Suppression **
- Mess with nucleic acid / DNA synthesis
- Folate also needed by rapidly-dividing cells.
2
Q
Imatinib
Mech (2 Genes), Uses (2)?
A
MECH: Tyrosine Kinase inhibitor of:
- bcr-abl (CML)
- c-kit (GI stromal tumors)
USES:
- CML
- GI stromal tumors
