MSK Flashcards

0
Q

Chronic Gout due to uric acid OVERPRODUCTION (2)

A

Xanthine Oxidase Inhibitors: Allopurinol + Febuxostat

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1
Q

Chronic Gout due to uric acid UNDEREXCRETION

A

Probenecid

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2
Q

Acute Gout / Gout-related Infl (3)

A
  • NSAIDs (ie Indomethacin)
  • Colchicine
  • Glucocorticoids
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3
Q

Arthritis in patients with Gastritis or Gastric Ulcers

A

Celecoxib

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4
Q

Osteoarthritis

A

Celecoxib

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5
Q

RA (5: 2 Onc + 1 GI + 2 MSK)

A
  • Methotrexate
  • 6-MP
  • Sulfasalazine
  • Celecoxib
  • TNF-a Inhibitors (Etanercept + Adalimu-/Infliximab)
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6
Q

SLE (5)

A
  • 6-MP
  • Hydroxychloroquine
  • Immunosuppressants
  • NSAIDs
  • Steroids
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7
Q

Fibromyalgia (3)

A
  • Regular exercise
  • Antidepressants (TCAs + SNRIs)
  • Anticonvulsants
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8
Q

Myosites

A

Steroids

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9
Q

Osteoporosis (3)

A
  • Bisphosphonates (-dronates)
  • Denosumab
  • Raloxifene
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10
Q

Paget Disease of Bone

A

Bisphosphonates (-dronates)

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11
Q

Ankylosing Spondylitis

A

TNF-a Inhibitors (Etanercept + Adalimu-/Infliximab)

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12
Q

Ewing Sarcoma

A

Dactinomycin

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13
Q

TNF-a Inhibitors (Etanercept + Adalimu-/Infliximab)

Mech, Uses (4)?

A

MECH: Prevention of Macrophage activation => Prevention of destruction of phagocytosed microbes.

USES:

  • RA
  • Ankylosing Spondylitis
  • Psoriasis (Adalimumab)
  • Crohn’s (Infliximab)
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