MSK Flashcards
0
Q
Chronic Gout due to uric acid OVERPRODUCTION (2)
A
Xanthine Oxidase Inhibitors: Allopurinol + Febuxostat
1
Q
Chronic Gout due to uric acid UNDEREXCRETION
A
Probenecid
2
Q
Acute Gout / Gout-related Infl (3)
A
- NSAIDs (ie Indomethacin)
- Colchicine
- Glucocorticoids
3
Q
Arthritis in patients with Gastritis or Gastric Ulcers
A
Celecoxib
4
Q
Osteoarthritis
A
Celecoxib
5
Q
RA (5: 2 Onc + 1 GI + 2 MSK)
A
- Methotrexate
- 6-MP
- Sulfasalazine
- Celecoxib
- TNF-a Inhibitors (Etanercept + Adalimu-/Infliximab)
6
Q
SLE (5)
A
- 6-MP
- Hydroxychloroquine
- Immunosuppressants
- NSAIDs
- Steroids
7
Q
Fibromyalgia (3)
A
- Regular exercise
- Antidepressants (TCAs + SNRIs)
- Anticonvulsants
8
Q
Myosites
A
Steroids
9
Q
Osteoporosis (3)
A
- Bisphosphonates (-dronates)
- Denosumab
- Raloxifene
10
Q
Paget Disease of Bone
A
Bisphosphonates (-dronates)
11
Q
Ankylosing Spondylitis
A
TNF-a Inhibitors (Etanercept + Adalimu-/Infliximab)
12
Q
Ewing Sarcoma
A
Dactinomycin
13
Q
TNF-a Inhibitors (Etanercept + Adalimu-/Infliximab)
Mech, Uses (4)?
A
MECH: Prevention of Macrophage activation => Prevention of destruction of phagocytosed microbes.
USES:
- RA
- Ankylosing Spondylitis
- Psoriasis (Adalimumab)
- Crohn’s (Infliximab)
