Renal Regulation of ECF Potassium

Question 1

High pH causes a shift of potassium ions into ____ from the ECF.

Answer 1

all cells

Question 2

What cells synthesize aldosterone?

Answer 2

adrenal zona glomerulosa cells

Question 2

______ increases potassium secretion, hence tends to produce hypokalemia.

Answer 2

Alkalosis

Question 3

All of the filtered potassium is ______ reabsorbed, hence regulated potassium secretion in the fine tuning segments also determines potassium excretion and ECF potassium balance.

Answer 3

obligatorily

Question 3

Alkalosis increases ______ secretion, hence tends to produce ______.

Answer 3

potassium; hypokalemia

Question 5

What happens when the ECF concentration of K+ increases?

Answer 5

K+ is pumped into the cell AND the adrenal cortex cells are stimulated to release aldosterone

Question 6

What do the principal cells do?

Answer 6

they move potassium from the serosa to lumen of the fine tuning segments

Question 8

All of the filtered potassium is obligatorily reabsorbed, hence regulated potassium secretion in the fine tuning segments also determines potassium _____ and _____.

Answer 8

excretion; ECF potassium balance

Question 9

How does aldosterone increase K secretion?

Answer 9

increases the number of Na/K/ATPase pumps on the basolateral surface and the # of apical K and Na channels

Question 10

Alkalosis ______ potassium secretion, hence tends to produce ______.

Answer 10

increases; hypokalemia

Question 11

____ causes a shift of potassium ions into all cells from the ECF.

Answer 11

High pH