Renal - PowerPoint/2 Flashcards
ARF can be caused by
4
- severe shock
- burns
- nephrotoxins
- acute bilateral kidney infection/inflammation
CKD with low vit D synthesis and hypocalcemia can lead to
fractures
AKI maintenance phase - what increase
2
- serum creatinine
2. blood urea nitrogen
AKI recovery phase - what is common
diuresis
CKD acid-base balance
metabolic acidosis when GFR 30-40%
AKI recovery phase - what is increased
1
creatinine clearance
AKI phase where serum creatinine and blood urea nitrogen are both increased
maintenance
ARF stands for
acute renal failure
CKD
progressive loss of renal function that affects nearly all organ systems
AKI postrenal occurs with
urinary tract obstructions that affect the kidneys bilaterally
AKI phase where established kidney injury and dysfunction are present
maintenance
CKD - sodium and water balance; what diminishes
concentration and dilution ability
CKD mod stage
GFR 30-59
CKD - what falls
GFR falls
clinical sx that point to CKD
4
- proteinuria
- uremia
- decreased GFR
- increased creatinine in plasma
AKI caused by impaired renal blood flow
prerenal
CRF can be caused by
4
- nephrosclerosis
- DM
- nephrotoxins
- polycystic disease
AKI - postischemic is to
ATN intra
CKD neuro sx
3
- lethargy
- seizures
- coma
ATN stands for
acute tubular necrosis
AKI - occurs with urinary tract obstructions that affect the kidneys bilaterally
post renal
CKD stages
5
- normal
- mild
- mod
- severe
- end stage
CKD end stage
GFR < 15
AKI prerenal is caused by
impaired renal blood flow
CKD severe stage
GFR 15-29
CKD potassium balance (tubular)
tubular secretion increases early
CKD sodium and water balance
sodium excretion increases with water excretion leading to sodium deficit and volume loss
AKI phase where urine output is lowest
maintenance
CKD - decreased renal synthesis of
2
- vit D
2. hypocalcemia
AKI phase where kidney injury is evolving
initiation
AKI recovery phase - what is declined
2
- serum creatinine
2. urea
CKD - plasma what increases
creatinine
CKD cardiovascular sx
3
- HTN
- pericarditis
- heart failure
AKI recovery (polyuric) phase
injury repair and normal renal function reestablish
CKD skin sx
6
- pallor
- sallow pigmentation
- bruising
- nail changes
- ‘frost’
- pruritic
CKD metabolism issues
abnormal protein, carb, and fat metabolism
AKI stands for
acute kidney injury
AKI intra sx
oliguria
most common cause of ARF
prerenal AKI
AKI intrarenal - what is the most common cause of intrarenal renal failure
acute tubular necrosis ATN
CRF early sx
4
- polyuria w/ dilute urine
- anemia
- fatigue
- HTN
CKD urine and blood results
4
- proteinuria
- uremia
- creatinine clearance falls
- urea clearance falls
CKD - alterations are seen in the following systems
9
- cardiovascular
- pulmonary
- hematologic
- immune
- neurologic
- GI
- endocrine
- reproduction
- integumentary
AKI prerenal GFR
GFR declines because of the decrease in filtration pressure
progressive loss of renal function that affects nearly all organ systems
CKD
frost and sallow pigmentation is to
CKD
AKI initiation phase
2
- kidney injury is evolving
2. prevention of injury is possible
CKD - once oliguria sets in, what is retained
potassium
CKD proteinuria and uremia due to
glomerular hyperfiltration
CKD anemia sx
3
- lethargy
- dizziness
- low hematocrit
CKD mild stage
GFR 60-89
AKI ATN can be caused by (intra)
2
- postischemic
2. nephrotoxic
AKI prerenal aka
ischemia
AKI - nephrotoxic is to
ATN intra
CKD normal stage
GFR > 90 mL/min
ARF early sx
2
- oliguria
2. increased serum urea
CKD phosphate excretion
reduced
CKD stands for
chronic kidney disease
AKI maintenance (oliguric) phase - there is established what? 2
- kidney injury
2. dysfunction
AKI maintenance phase - what is lowest during this phase
urine output
AKI can be caused by
- renal insufficiency
- renal failure
- end stage renal failure ESRF
AKI ATN is to
intrarenal
AKI phases
3
- initiation
- maintenance (oliguric)
- recovery (polyuric)
CKD is associated with what sx
3
- HTN
- diabetes
- intrinsic kidney disease
AKI - GFR declines because of the decrease in filtration pressure is to
prerenal
AKI prerenal - severe shock causes
vasoconstriction and decreased blood flow