Renal - Class Notes/1 Flashcards
nephrotic hallmark sx
massive loss of protein
renin function
converts angiotensinogen to angiotensin 1, lungs then convert Ang-1 to Ang-2 for vasoconstriction
two systemic disease that cause glomerulonephritis
- HTN
2. DM
pushing out pressure =
HP
post strep infection can cause
2
- RHD
2. glomerulonephritis
AKI that is uncontrolled can lead to
3
- renal insufficiency
- renal failure
- ESRF
nephrotic or nephritic - massive loss of protein
nephrotic
AKI post think
obstruction in uriter
AKI most common outcome
resolution
kidney edema causes
2
decreased albumin
decreased OP
nephrotic or nephritic - not immune related
nephrotic
AKI prerenal is to
impaired renal blood flow
glomerulonephritis proteinuria level
massive, >3g/day
3 processes of urinary system
- filtration
- reabsorption
- excretion
AKI intra most common causes
2
- post ischemic
2. nephrotoxic
liver edema causes
2
decreased albumin
decreased OP
glomerulonephritis tx
restrict protein, sodium, and water
glomerulonephritis - if there are RBC casts, where is the bleeding coming from
kidney - distal tubule
glomerulonephritis tx of choice
high dose steroids
most common cause of glomerulonephritis
post strep infection
CKD two fates
- slow decline
2. fast decline
how do you r/o post strep infection of glomerulonephritis
strep test
three main systems affected from CKD
heart
liver
NS
what two things should not be filtered out in urine
- RBCs
2. Protein
nephrotic - glomerulus is more
permeable
AKI - prerenal….think
3
- heart
- bvs
- hypoperfusion
AKI - shock is to
pre
CKD is a what loss of function
progressive
CKD sx
2
- proteinuria
2. uremia (can be converted to ammonia and cause encephalopathy)
post strep infection suspected to cx glomerulonephritis - what to ask patient
how have you been feeling the past few months
most common immunological cause of glomerulonephritis (general)
post infection
nephritic is to
glomerulus inflammation
nephrotic dx test
urinalysis; 24 hour urine collect, keep urine cold
AKI intra is to
acute tubular necrosis ATN
CKD is classified by
GFR >90 (n. 125)
cardio edema causes
increase HP
what drugs can cause glomerulonephritis
4
- ibuprohin
- NSAIDs
- drugs to tx pneumonia
- drugs to tx heart disease
3 organs you think of when you hear edema
heart
liver
kidney
ATN is to
AKI intra
AKI intrarenal px makeup
3
- alcoholic and homeless
- depression w/ OD of OTC meds
- cancer px from tx
CKD lab tests important results
2
increased BUN and creatinine
CKD - when do we worry about GFR
<50
AKI - think…
3
pre
intra
post
nephrotic is not what related
immune
two common causes of CKD
HTN
DM
glomerulonephritis what happens in type II hypersensitiivty
in situ; body attacks the basement membrane
pulling in pressure =
OP
