Renal - PowerPoint/1 Flashcards

1
Q

nephrotic or nephritic syndrome - HTN

A

nephritic

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2
Q

inflammation of the glomerulus

A

flomerulonephritis

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3
Q

glomerulonephritis blood tests results reveal elevated what

6

A
  1. serum urea
  2. creatinine
  3. anti-DNase B
  4. strept Abs
  5. antistreptolysin
  6. antistreptokinase
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4
Q

increased renin secretion and decreased GFR leads to

A

increased BP

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5
Q

nephrotic or nephritic syndrome - azotemia

A

nephritic

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6
Q

glomerulonephritis leads to elevated BP that is caused by

2

A

increased renin secretion and decreased GFR

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7
Q

nephrotic or nephritic syndrome - hyperlipidemia and lipiduria

A

nephrotic

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8
Q

glomerulonephritis - urine becomes

2

A

dark

cloudy

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9
Q

oliguria, HTN, and edema are sx of

A

glomerulonephritis

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10
Q

hyperlipidemia and lipiduria

A

nephrotic syndrome

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11
Q

oliguria, HTN, and variable proteinuria is to

A

nephritic syndrome

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12
Q

glomerulonephritis mechanism of injury - deposition of circulating what?

A

soluble Ag-Ab complexes, often with complement fragments (type III hypersensitivity)

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13
Q

nephrotic syndrome protein excretion is caused by

A

glomerular injury

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14
Q

nephritic syndrome proteinuria value

A

< 3g/day

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15
Q

glmerulonephritis can be caused by

5

A
  1. immunology
  2. drugs/toxins
  3. vascular disorders
  4. systemic disease (secondary)
  5. viral
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16
Q

vit D def is to

A

nephrotic syndrome

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17
Q

nephrotic or nephritic syndrome - oliguria

A

nephritic

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18
Q

glomerulonephritis drug tx

2

A
  1. glucocorticoids for inflammation

2. antihypertensives

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19
Q

hypoalbuminemia with edema

A

nephrotic syndrome

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20
Q

nephritic syndrome sx

5

A
  1. hematuria
  2. azotemia
  3. oliguria
  4. HTN
  5. variable proteinuria
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21
Q

glomerulonephritis mechanisms of injury include

3

A
  1. deposition of Ag-Ab complexes into basement membrane
  2. Abs acting against Ags planted in the glomerulus
  3. non immune factors i.e. drugs, toxins, ischemia
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22
Q

elevated serum urea and creatinine levels are signature for

A

glomerulonephritis

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23
Q

nephrotic or nephritic syndrome - proteinuria > 3.5g/day

24
Q

glomerulonephritis two major symptoms if severe are

A
  1. hematuria w/ RBC casts

2. proteinuria >3.5 g/day w/ albumin as the major protein

25
excretion of > 3.5 g of protein in the urine per day
nephrotic syndrome
26
glomerulonephritis mechanism of injury - Abs reacting ...
in situ against planted Ags within the glomerulus (type II hypersensitivity - cytotoxic)
27
nephrotic syndrome
excretion of > 3.5 g of protein in the urine per day
28
nephrotic syndrome proteinuria level
>3.5g/day
29
glomerulonephritis causes pain where | 2
flank | back
30
glomerulonephritis edema happen where initially? | 2
initially, facial and periorbital edema - then general edema follows
31
glomerulonephritis tx | 3
1. sodium restriction 2. protein and fluid intake decreased 3. drugs
32
glomerulonephritis
inflammation of the glomerulus
33
hematuria with RBC casts is to
severe glomerulonephritis symptom
34
nephrotic or nephritic syndrome - hypoalbuminemia < 3.5
nephrotic
35
proteinuria > 3-5g/day with albumin (macroalbuminuria) as the major protein in urine is to
severe glomerulonephritis symptom
36
nephrotic or nephritic syndrome - edema
nephrotic
37
most common infection that leads to glomerulonephritis
strep infections
38
nephrotic and nephritic sediment are sx of
glomerulonephritis
39
glomerulonephritis - metabolic _____
acidosis
40
edema and stretching of the renal capsule lead to | 2
1. flank pain | 2. back pain
41
glomerulonephritis urinalysis results | 4
1. proteinuria 2. hematuria 3. erythrocyte casts 4. no infection
42
nephrotic syndrome hypoalbuminemia level
< 3.5g/dL
43
nephrotic or nephritic syndrome - hematuria
nephritic
44
glomerulonephritis mechanisms of injury - type II hypersensititivty (cytotoxic)
Abs reacting in situ against planted Ags within the glomerulus
45
glomerulonephritis BP
elevated
46
azotemia is to
nephritic syndrome
47
most common cause of glomerulonephritis
immunologic abnormalities
48
glomerulonephritis blood tests results reveal decreased what | 1
1. complement levels
49
glomerulonephritis manifestations include | 9
1. hematuria 2. RBC casts 3. proteinuria 4. macroalbuminuria 5. oliguria 6. HTN 7. edema 8. nephrotic sediment 9. nephritic sediment
50
glomerulonephritis mechanism of injury - type III hypersensitivity
deposition of circulating soluble Ag-Ab complexes, often with complement fragments
51
hematuria with dysmorphoc RBCs and RBC casts
nephritic syndrome
52
dark and cloudy urine is to
glomerulonephritis
53
nephrotic syndrome findings include | 5
1. hypoalbuminemia 2. edema 3. hyperlipidemia 4. lipiduria 5. vitamin D deficiency
54
nephrotic or nephritic syndrome - proteinuria < 3 g
nephritic
55
nephritic syndrome - hematuria | 2
dysmorphic RBCs, RBC casts also
56
azotemia
high nitrogen compounds in blood
57
glomerulonephritis - flank and back pain from | 2
1. edema | 2. stretching of renal capsule