Ch. 36 GI - Book/6 Flashcards

1
Q

hypovolemia, hypotension, and shock are sx of

A

acute pancreatitis

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2
Q

pancreatitis develops because of

A

obstruction to the outflow of pancreatic digestive enzymes caused by bile and pancreatic duct obstruction

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3
Q

goal of tx for acute pancreatitis is to

2

A

stop process of autodigestion and prevent systemic complications

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4
Q

pancreatitis that is usually mild and resolves spontaneously

A

acute

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5
Q

epigastric or midabdominal constant pain that radiates to back

A

pancreatitis

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6
Q

common age for pancreatitis

A

50-60

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7
Q

chronic pancreatitis pain is associated with

5

A
  1. increased intraductal pressure
  2. ischemia
  3. neuritis
  4. intra-abdominal HTN
  5. ongoing injury
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8
Q

abdominal distention with bowel hypomotility is to

A

acute pancreatitis

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9
Q

risk factor for pancreatic cancer

A

chronic pancreatitis

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10
Q

characteristics lab finding for acute pancreatitis

A

elevated amylase

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11
Q

elevated serum lipase levels is to

A

primary dx marker for acute pancreatitis

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12
Q

what increase the risk for chronic pancreatitis (besides alcohol)
3

A
  1. obstruction from gallstones
  2. smoking
  3. genes
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13
Q

pancreatitis pain is caused by

4

A
  1. edema
  2. chemical irritation and inflammation of peritoneum
  3. irritation or obstruction of the biliary tract
  4. inflammation of nerves
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14
Q

acute pancreatitis complications can include

6

A
  1. ARDS
  2. heart failure
  3. renal failure
  4. coagulopathies
  5. intra abdominal HTN
  6. systemic inflammatory response syndrome SIRS
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15
Q

chronic pancreatitis is a process of

A

progressive fibrotic destruction of the pancreas

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16
Q

pancreatitis risk factors

8

A
  1. obstructive biliary tract disease
  2. alcoholism
  3. obesity
  4. peptic ulcers
  5. trauma
  6. hyperlipidemia
  7. hypercalcemia
  8. smoking
17
Q

progressive fibrotic destruction of the pancreas

A

chronic pancreatitis

18
Q

chronic pancreatitis - what contribute to the destruction of acinar cells and islets of langerhans
2

A
  1. toxic metabolites

2. chronic release of inflammatory cytokines

19
Q

elevated amylase is to

A

acute pancreatitis

20
Q

pancreatitis - what accompany the inflammatory response

2

A

fever

leukocytosis

21
Q

chronic pancreatitis - may be required to relieve pain and prevent cystic rupture
2

A

endoscopic or surgical drainage of cysts or partial resection of pancreas

22
Q

develops because of obstruction to the outflow of pancreatic digestive enzymes caused by bile and pancreatic duct obstruction

A

pancreatitis

23
Q

inflammation of the pancreas aka

A

pancreatitis

24
Q

which pancreatitis can lead to DM

A

chronic

25
Q

systemic effects of acute pancreatitis are related to

A

release of proinflammatory cytokines into the bloodstream

26
Q

acute pancreatitis can result from direct cell injury from

3

A

alcohol
drugs
virus

27
Q

most common cause of chronic pancreatitis

A

chronic alcohol abuse

28
Q

acute pancreatitis tx - to decrease pancreatic secretion and rest the gland, what may be done initially

A

stop oral intake

29
Q

because of obstruction, what happens to the pancreas

A

activated enzymes cause autodigestion of pancreatic cells and tissues, resulting in inflammation

30
Q

the cardinal manifestations of acute pancreatitis is

A

epigastric or midabdominal constant pain that radiates to back

31
Q

primary dx marker for acute pancreatitis

A

elevated serum lipase levels

32
Q

acute pancreatitis - what occurs because plasma volume is lost as inflammatory mediators release into the circulation and dilate vessels
5

A
  1. hypovolemia
  2. hypotension
  3. tachycardia
  4. myocardial insufficiency
  5. shock
33
Q

chronic pancreatitis is a risk factor for

A

pancreatic cancer

34
Q

common sx of chronic pancreatitis

2

A
  1. continuous or intermittent abdominal pain

2. weight loss

35
Q

chronic pancreatitis - to correct enzyme deficiencies and prevent malabsorption, what is done

A

oral enzyme replacements are taken before and during meals

36
Q

manifestations of what are present in late stages of chronic pancreatitis

A

pancreatic enzyme deficiency