renal outflow disease Flashcards

1
Q

what diseases of the urinary tract can occur?

A
UTI
urinary tract obstruction
-renal stones
-tumour
-prostate hypertrophy
urinary tract malignancy
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2
Q

how do UTI’s occur?

A
urine sterile
any bacteria implies infection
usually from bacteria contamination from skin around urethra
white cells in urine indicate infection
blood in urine
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3
Q

how is sterile urine collection done?

A

through abdominal wall

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4
Q

how should a urine sample be collected?

A

mid-stream

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5
Q

describe UTI

A
more common in women
-shorter urethra
usually E.coli
-predominant organism in area
predisposing factors
-poor bladder emptying
-low urinary flow rates
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6
Q

what is cystitis?

A

bladder infection

uti can proceed

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7
Q

what are the symptoms of UTI?

A
dysuria
urinary frequency
cloudy urine
offensive smelling urine
supra-pubic pain
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8
Q

what can infected urine cause?

A
cystitis
renal infection
-reflux to kidneys
-normal emptying void downward-muscles should close off end to ureter
prostate infection
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9
Q

what is UTI tx?

A

diagnosis
increase fluid intake
frequent urination
occasionally antibiotics

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10
Q

what can cause urinary tract obstruction?

A
renal calculi
prostatic disease
-hypertrophy
-prostatic malignancy
urinary tract strictures
external compression
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11
Q

why does prostate disease make urination difficult?

A

urethra passes through prostate gland on way to penis

narrowed urethra

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12
Q

describe prostate disease

A
prostatitis
-inflammation of prostate
benign prostatic hypertrophy
-almost normal
-hyperplasia of prostate
prostatic cancer
-adrenocarcinoma
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13
Q

what are the symptoms of urine outflow obstruction?

A
slow stream
hesitancy
frequency
urgency
nocturia
incomplete voiding
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14
Q

what is the treatment of benign prostatic hypertrophy?

A
initially drug based
-a-blocking drugs
-anticholinergic
-diuretics
surgery-prostatectomy
-open
-robot assisted
-transurethral prostatectomy
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15
Q

describe prostatic malignancy occurance

A
starts >45 y/o
90% men >90yrs at autopsy
most asymptomatic
2nd most common male cancer
89% 5 yr survival
63% 10 yr survival
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16
Q

describe prostate cancer screening

A
PSA blood test not always diagnostic
-prostatic specific antigen
-specificity/sensitivity problem
-useful for monitoring
mpMRI
-ealy detection
17
Q

describe prostatic malignancy tx

A
surgery
-radical prostatectomy
radiotherapy
hormone tx
-anti-androgens & LHRH analogues
-block hormone-dependent tumour growth
widespread bone metastasis
18
Q

describe renal calculi

A
5% population
-kidney/bladder
extremely painful passing
different stone types
-Ca/oxalate radiopaque
-uric acid not radiopaque
treat with lithotripsy
-sound waves break stones into fragments enabling them to pass