Renal Distal Tubule, Collecting Ducts And Urination Flashcards
What is the surrounding interstitial fluid of the renal cortex conc
300 mosmol/l
The distal tubule and the collecting duct are major sites for…..
Regulation of ion and water balance
What does ADH vasopressin do in the collecting duct
-increase water reabs
Reducing urinary output
What does aldosterone do to the collecting duct
Increases sodium reabs
Increases hydrogen ion and pottasium secretion
PRIMARY HORMONE FOR SALT BALANCE
What does atrial natriuretic hormone do in the collecting ducts
Decrease sodium reabs
What does parathyroid hormone do in the collecting duct
Increase calcium reabs
Decrease phosphate reabs
The distal tubule can be split into
An early and late section
What happens in the early state of the distal tubule
Sodium chloride reabs
What happens int he late distal tubule
Calcium reabs
Hydrogen ion sec
Sodium reabs
Pottasium reabs
What does the late collecting duct have
Low ion perm
Perm to water influenced by ADH
Where is ADH produced
Syn by neurones in supraoptic nucleus in the hypothalamus then from post pit
It is a neurohormone
He does ADH affect the collecting duct
Vasopressin –> type 2 vasopressin receptor –> conv atp to cAMP –> insert aquaporins –> increases water move into cell
What happens if there is is a high ADH comic in the plasma
High water perm
Hypertonic urine
What happens if there is slow ADH conc in the plasma
Low water permeability
Hypotonic urine
What happens to the urine osmolarity as the ADH conc in plasma increases
It increases
