Ovary And Testis Flashcards

1
Q

Where does oogenesis begin

A

In utero

Mitosis division of oogonia

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2
Q

At what stage does the oogonia arrest

A

Prophase where suspended for many years and begins again prior to ovulation
Completed at fertilisation

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3
Q

What is the first polar body

A

One of two products in the first stage of meiosis

Both relatively small and little cytoplasm

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4
Q

What does the presence of two polar bodies signify

A

Spermatogenesis entry and the completion of second meiotic division

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5
Q

How long does the average menstrual cycle last

A

28 days

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6
Q

How many stages are in the menstrual cycle and what are they

A

2 stages
Follicular phase
Lateral phase

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7
Q

What roughly happens in the follicular phase

A

Maturation of the egg
Ready for ovulation at mid cycle
Occupation signals end of follicular phase

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8
Q

What roughly happens in the literal phase

A

Development of the corpus luteum

Induces prep of reproductive tract for pregnancy if fertilisation occurs

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9
Q

What is a corpus luteum

A

A hormone secreting structure that develops in an ovary
after an ovum has been discharged after a few days unless pregnancy has begun

Secretes volumes of progesterone and oestrogens making uterus more favourable for implantation

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10
Q

What is GnRH and where is it produced and what does it do

A

Gonadotropin releasing hormone
Syn by neurones in hypothalamus
Pulsatile release

Stim FSH and LH syn/release form ant pit

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11
Q

What is FSH, where is it produced and what does it do

A

Follicle stim hormone
Secreted by ant pit
Stimulates follicular development
Thickens endometrium

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12
Q

What is LH, where is it produced and what does it do

A
Luteinising homone 
Sec by ant pit
Peak stim at ovulation 
Stimulates corpus luteum development 
Thickend endometrium
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13
Q

Where is oestrogen primarily sec form

A

Ovaries
Adrenal cortex
Placenta when pregnant

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14
Q

What does oestrogen do

A

Thicken endometrium

Prod fertile cervical mucus

Mature ovarian follicles

Responsible for secondary sexual characteristics

Accelerate sodium and water reabs by kidney tubules

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15
Q

What does a high or low level of oestrogen do

A

High - inhibits sec of FSH and prolactin stimulates LH

Low - after pregnancy, stimulates secretion of prolactin

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16
Q

What sec progesterone

A

Corpus luteum and placenta when pregnant

17
Q

What does progesterone do

A

Inhibit LH sec

Thermogenin effect

Relaxes smooth muscle

Infertile mucus

Maintain thickness of endometrium

Maintain pregnancy

18
Q

What is the follicular phase in full

A

Follicular development stimulated –> follicle makes follicular fluid which has estrogen –> thicken endometrium –> increase of estrogen inhib FSH and increase LH –> LH stimulates ovulation and initiates development of corpus luteum

19
Q

What is the luteal phase in full

A

Follows ovulation –> ruptured follicle cavity is replaced by corpus luteum( sec or gesturing and estrogen) –> progesterone stim changes in endometrium for impnatation during early phase of pregnancy –> if fertilisation doesn’t happen curious luteum regress and prod progesterone and estrogen decreases

20
Q

What is the menstrual phase in full

A

Corpus luteum regresses
Progesterone and estrogen decreases
Endometrium degenerates and menstraujtion occurs
Drop of estrogen in blood and progesterone causes a stim production of FSH which starts cycle again

21
Q

What is the LH surge

A

Oocyte resumes meiosis
Secondary oocyte + polar body (degenerates)
Stops at metaphase II only co,pelted if fertilised
Cytoplasmic maturation
LH receptors stimulated to synthesise orgiesteorne
Collapsed follicle becomes corpus luteum

22
Q

What colour is lutein

A

Yellow/orange carotenoid pigment

23
Q

What is the route of sperm

A

Testes –> epididymis –> vas deferens –> ejaculatory duct –> urethra

24
Q

Where does spermatogenesis occur and when

A

Within seminiferous tubules of testes
Germ cell mitosis re activated at puberty
Constant

25
What hormones control the testes
LH --> acts on leydig cells - reg testosterone sec FSH --> act of Sertoli cells to enhance spermatogenesis essential for spermatid remodelling LH and FSH release stimulated by GnRH
26
Where are the Sertoli cells and what do they secrete
In the seminiferous tubule | Sec androgen binding globulin and inhibin
27
What are some adverse effects on human spermatogenesis
``` Heat Alcohol Smoking Chemo/radiotherapy Vasectomy ```
28
What are the two major differences between oogenesis and spermatogenesis
- oogenesis prod one ovum, spermatogenesis prod millions of sperm - once a month p, spermatogenesis constant
29
What does a high level of FSH mean
Loss of ovarian function | Menopause
30
What is the production of eggs and sperm
Eggs - oogenesis Sperm - spermatogenesis