Renal Acid Base Mechaninsms Inv In Reg Of Hydorgen Ions In Plasma Flashcards
What can acidosis and alkalosis lead to
Acidosis - depression of cns
Alkalosis - over excitability of pNS and later CNS
What can hydrogen ions do to enzymes and pottasium levels
Marked influence on enzyme activity
Influence pottasium levels
How are hydrogen ions added
Carbonic acid formation
Inorganic acids produced during breakdown of nutrients
Organic acids resulting form metabolism
What is the Henderson hasselbach equation
PH = pk + log(a)/(ha)
A= base Ha = acid
What is the most important buffer physiological system
Co2-HCo3 buffer
How is carbonic acid formed
Carbon dioxide plus water with the action of carbonic anhydrase forms carbonic acid
What is the role of the kidney in control of the plasma concentration of bicarbonate
Variable reabs of filtered bicarbonate
Kidneys can add new bicarbonate to the blood which is imp to treat acidosis
What su another buffer
Phosphate
The excess amount of hydrogen excreted as hydrogen phosphate can be measured as
Titratable acid
Action of ammonia as a tubular buffer
Acid excreted as ammonium
New bicarbonate formed
The vast majority of hydrogen ion secretion used for
Bicarbonate reabs to prevent acidosis
Excretion of tetra table acid and ammonium
Rudd the body simultaneously of acid load and regen buffer stores
What is the ph of blood
7.4
