RENAL Flashcards
0
Q
Diuretics (3)
A
- Dehydration
- Hypokalemia (except for K-sparing diuretics)
- Hepatic Encephalopathy (due to↓NH3 removal -> NH3 toxicity)
1
Q
Mannitol (1)
CI (2)?
A
Pulmonary Edema
CI:
- CHF
- Anuria
2
Q
CA Inhibitors
A
RTA 2
3
Q
Loop Diuretics (Furosemide + Ethacrynic acid)
(6: “OH DANG”), CI (2)?
A
- “OH DANG” *
O- Ototoxicity H- Hypokalemia D- Dehydration A- Allergy (Sulfa) N- Nephritis (Interstitial) G- Gout (can cause hyperuricemia)
CI:
- NSAIDs (opposing effects on PGE -> no dilation of A.A -> Interstitial Nephritis)
- Gout patients
4
Q
Thiazides
(5: 4 “HyperGLUC” + 1)?
A
- Hyperglycemia
- Hyperlipidemia
- Hyperuricemia
- Hypercalcemia
- Torsades de Pointes / Prolonged QT
5
Q
Thiazides + Furosemide
A
Gout
6
Q
K-Sparing Diuretics
A
RTA 4
7
Q
ACE Inhibitors
(6: THINK: “Captopril’s CATCHH”), CI (2)?
A
- Cough (due to↑Bradykinin)
- Angioedema
- Teratogen (-> fetal renal malformation)
- Creatinine (↓GFR)
- Hypotension
- Hyperkalemia
CI:
- C1-Esterase Inhibitor Def (Complement Def)
- Renal artery stenosis (b/c constrict efferent arterioles ->↓GFR -> renal failure in these patients)
8
Q
Drug that causes Antiandrogen effects / Gynecomastia?
A
Spironolactone
9
Q
Drugs that cause Diabetes Insipidus
(2)?
A
- Demeclocycline
- Lithium
10
Q
Drug that causes Fanconi’s Sx?
A
EXPIRED Tetracycline
11
Q
Drugs that cause Hemorrhagic Cystitis
(2: “—famide”)?
A
- Cyclophosphamide
- Ifosfamide
12
Q
Drugs that cause Interstitial Nephritis
(3)?
A
- NSAIDs
- Furosemide
- Methicillin
12
Q
Drugs that cause RTA Type 1
A
Amphotericin B toxicity
14
Q
Drugs that cause SIADH
(2)?
A
- Carbamazepine
- Cyclophosphamide
