HEME

Question 0

Aspirin

(6)?

Answer 0

• Hemolysis in G6PD-deficient patients
• Reye’s Sx: Children with viral infection who take Aspirin
• Tinnitus (CN 8)
• Hyperventilation (due to its acidity)
• Gastric Ulceration + Upper GI Bleeding (due to its PGE1 inhibition)
• Interstitial Nephritis + Renal Ischemia / Acute Renal Failure
  (due to its PGE1 inhibition)

Question 1

Anticoagulants

(2)?

Answer 1

• Priapism

- Subdural Hematoma

Question 2

Heparin

(2)?

Answer 2

• Heparin-Induced Thrombocytopenia

- Osteoporosis

Question 3

Drugs that cause Agranulocytosis

(6: “Agranulocytosis Could Certainly Cause Pretty Major Damage”)?

Answer 3

• Colchicine
• Carbamazepine
• Clozapine
• Propylthiouracil
• Methimazole
• Dapsone

Question 4

Drugs that cause Aplastic Anemia

(5)?

Answer 4

• NSAIDs
• Benzene
• Propylthiouracil
• Chloramphenicol
• Methimazole

Question 5

Drug that causes Direct Coombs + Hemolytic Anemia?

Answer 5

Methyldopa

Question 6

Drug that causes Gray Baby Sx?

Answer 6

Chloramphenicol

Question 7

Drugs that cause Hemolysis in G6PD-Deficient Patients

(6: “Hemolysis IS PAIN”)?

Answer 7

• Isoniazid (INH)
• Sulfonamides
• Primaquine
• Aspirin
• Ibuprofen
• Nitrofurantoin

Question 8

Drugs that cause Hemolytic Anemia

(3: 2 Antibiotics + 1 Antiviral)?

Answer 8

• Penicillin
• Sulfonamides (if G6PD def)
• Ribavirin

Question 9

Drugs that cause Megaloblastic Anemia

(4: “Having a blast with PPMS”)?

Answer 9

• Phenytoin
• PPIs
• Methotrexate
• Sulfa drugs

Question 10

Drugs that cause Thromboses?

Answer 10

OCPs

Question 11

Drug Class that causes Thrombocytopenia

Answer 11

Class 1A Antiarrhythmics