ENDO Flashcards
1
Q
Glucocorticoids
(3: 2 + 1 from withdrawal)?
A
- Fat redistribution
- Myopathies
- (withdrawal) -> Adrenocortical insuf
2
Q
Propylthiouracil (4)
A
- Agranulocytosis
- Aplastic Anemia
- Hepatotoxicity
- Skin rash
3
Q
Methimazole
A
Agranulocytosis
4
Q
1st-Generation Sulfonylureas
A
Disulfiram-like reaction
5
Q
Glitazones / Thiazolidinediones (4)
A
- Edema
- Weight gain
- Heart failure
- Hepatotoxicity
6
Q
GLP-1 Analogs
A
Pancreatitis
7
Q
Metformin (2)
CI (2)?
A
- Lactic Acidosis (therefore CI in renal failure)
- GI upset
CI:
- Renal failure
- Use with contrast dyes (ie in imaging studies)
8
Q
Drug that causes Adrenocortical Insuf?
A
Glucocorticoid WITHDRAWAL (HPA suppression)
9
Q
Drugs that cause Cushing-like Sx
(2)?
A
- Prednisone
- Prednisolone
(Corticosteroids = #1 exogenous cause of Cushing’s. Lead to bilateral adrenal atrophy +↓ACTH secretion thr negative feedback.)
10
Q
Demeclocycline (3)
A
- Nephrogenic DI
- Bone / Teeth abnormalities
- Photosensitivity
11
Q
Drugs that cause Hyperglycemia
(4)?
A
- Diazoxide
- Niacin
- Protease Inhibitors
- Tacrolimus (immunosuppressant)
12
Q
Drugs that cause Hypothyroidism
(3)?
A
- Amiodarone
- Lithium
- Sulfonamides
