GI Flashcards
1
Q
Metoclopramide
A
Parkinson-like sx
2
Q
Cimetidine + Ranitidine
A
↑Bl Creatinine (by↓its renal excretion)
3
Q
PPIs (-prazole) (3)
A
- Pneumonia
- Risk of C difficile infection
- Hip fractures (↓serum Mg with long-term use)
4
Q
Misoprostol
A
Diarrhea
5
Q
Antacids (2)
A
- ↓stomach acid *
- Hypokalemia
- Chelation +↓effectiveness of other drugs (ie Tetracycline): alteration of gastric/urinary pH OR delaying of gastric emptying
6
Q
Cimetidine (3 Mech of Tox)
A
MECH OF TOX:
- Potent INHIBITOR of P450
- Antiandrogenic (ie gynecomastia, impotence,↓libido in males, prolactin release)
- BBB + BPB crossing
7
Q
Drugs that cause Pseudomembranous Collitis
(2)?
A
- Ampicillin
- Clindamycin
8
Q
Drugs that cause Cholesterol Gallstones
(2)?
A
- Bile Acid Resins
- Fibrates
9
Q
Drug that causes Reye’s Sx
A
Aspirin
10
Q
Therapy that causes 2ry Hemochromatosis
A
Chronic Transfusion Therapy
11
Q
Drug that causes Hepatitis
A
INH
12
Q
Drugs (+ 1 bug) that cause Hepatic Necrosis
(4)?
A
- Acetaminophen
- Halothane
- Valproic acid
- Amanita phalloides
13
Q
Drugs that cause Hepatic Adenoma
(2)?
A
- Anabolic Steroids
- OCPs
14
Q
Drug Classes that cause Acute Pancreatitis
(2)?
A
- Steroids
- Sulfa Drugs
15
Q
Drug class that causes Acute Cholestatic Hepatitis?
A
Macrolides
15
Q
HEPATOTOXIC Drugs
(6: 3 Antibiotics + 1 Antifungal + 2 Cardio)?
A
- Macrolides (Acute Cholestatic Hepatitis)
- INH
- Pyrazinamide
- Terbinafine (abnormal LFTs)
- Fibrates
- Statins
