Regulation of fuel use by insulin and glucagon Flashcards
what dies isnulin do to the uptake of glucose in cells
increases
what is glycogenesis
and what action does insulin have on this
formation of glycogen for storage
increases
what does insulin do to glycogenolysis
decreases (breakdown of glycogen to glucose)
What does insulin do to gluconeogenesis
decreases (formation of glucose from non-carbohydrate precurosrs)
what is the only hormone that decreases blood glucose levels
insulin
what does Akt do
-phosphorylates lots of different targets
-inhibits glycogen synthesis
-inhibits GSK3
-inhibits lots of transcription factors
Insulin can cause what to your weight
weight gain
what does Akt promote
promotes GLUT4 translocation to cell membrane
who needs a kick up the bum
the lecturer
Glucose makes its way into the cell by what transporter
GLUT 2
in the mitochondria, what stimulates ateyl coA
pyruvate
what does insulin raise
F2
6P
what does insulin do by raising F2 6P
allosterically raises gluconeogenesis and simultaneously activating glycolysis
anything insulin does, glucagon does the…
opposite
glucagon supresses what production
F2 6P
