Ogenesis, spermatogenesis, fertilisation, and implantation Flashcards

1
Q

where is testosterone produced

A

leydig cells

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2
Q

list 2 of the effects before birth testosterone has

A

masculinises reproductive tract and external genitalia
promotes descent of testes into the scrotum

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3
Q

list secondary sexual characteristics caused by testosterone

A

induces characteristic male pattern of hair growth
enlarges larynx
thickens skin
causes male body shape

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4
Q

what does testosterone do to the epiphyseal plates

A

closes them

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5
Q

where is sperm produced

A

seminiferous tubules

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6
Q

what types of cells support spermatogenesis

A

sertoli cells

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7
Q

recite the stages of sperm production in sertoli cells

A

spermatogonium
primary spermatocyte
secondary spermatocyte
spermatid
spermatozoa

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8
Q

what hormone is required for both stages (mitotic and meiotic)

A

testosterone

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9
Q

how many chromosomes does a primary spermatocyte have

A

46

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10
Q

ow many chromosomes does a secondary spermatocyte have

A

23

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11
Q

how many chromosones does a spermatid have

A

23

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12
Q

in what stage are spermatids produced

A

2nd meiotic division

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13
Q

in what stage are secondary spermatocytes produced

A

1st meiotic division

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14
Q

in what stage are primary spermatocytes produced

A

mitotic division

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15
Q

what hormone is required for the spermatids being converted to spermatozoa

A

FSH

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16
Q

what happens when spermatids are converted to spermatozoa

A

removal of unnecessary cellular components and rebuilding into specialised motile spermatozoa

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17
Q

what is the purpose of the acrosome

A

contains enzymes needed for penetration of the ovam

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18
Q

what cells are responsible for secretion of seminiferous tubule fluid

A

sertoli cells

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19
Q

what does inhibin do in spermatogenesis

A

regulates FSH secretion ( negative feedback loop)

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20
Q

what hormone rises in the menapause

A

FSH

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21
Q

what hormones fall in menapause

A

oestrogen, progesterone, and inhibin

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22
Q

what are the two phases in the ovarian cycle

A

follicular phase
luteal phase

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23
Q

in what phase does ovulation occur

A

follicular phase

24
Q

in what phase does the development of the corpus luteum occur

A

luteal phase

25
until puberty 1^0 follicles degenerate into what
scar tissue (atresia)
26
what does the follicular phase end with
ovulation
27
follicular cells left behind after ovulation undergo what
leutanisation (transformation into corpus luteum)
28
what hormones does the corpus luteum secrete
progesterone and oestrogen
29
after ovulation how many days does the corpus luteum grow
8-9 days
30
what forms if there is no fertilisation
corpus albicans
31
what signals the start of a new follicular phase
degeneration of the corpus luteum
32
if fertilisation occurs what hormones does the corpus luteum produce
oestrogen and progesterone
33
what days does oestrogen exert negative feedback
1-12 days
34
what days does oestrogen exert positive feedback
12-14 days
35
what causes the LH surge
positive feedback from oestrogen
36
without progesterone what happens to the uterine lining
sloughs off and then menstration occurs
37
what is the route of sperm
testes epidydmis vas deferens ejeaculatory duct urethra
38
freshly ejaculated sperm are not capable of ehat
fertilisation
39
what needs to happen before sperm are capable of fertilisation
capacitation
40
what happens when sperm go undergo capacitation
surface of sperm altered by removal of glycoprotein coat tail movements become whip like cAMP levels rise to promote acrosomal reactioon
41
fertilising sperm penetrate what in the egg
penetrate the corona radiata
42
what receptors do sperm bind to on the egg
ZP3
43
where are the ZP3 receptors
zona pellucida
44
binding to ZP3 triggers what
acrosome reaction
45
the sperm nucleus enters where
ovum cytoplasm
46
sperm stimulate release of what ion which inactivate ZP3
Ca2+
47
what chemical is released from the ovum to attract sperm
allurin
48
inactivation of the ZP3 receptors causes blocking of what
polyspermy
49
what cells are present on the blastocyst
trophoblast
50
how does the blastocyst implant on the uterine lining
cords of trophoblastic cells
51
what are the single layer of cells surrounding the blastocyst
trophoblast
52
how can you tell when implantation has finished
blastocyst is completely buried in the endometrium
53
what is the placenta derived from
trophoblast and decidual tissue
54
where is hCG produced from
blastocyst
55
what does hCG do to the corpus luteum
prolongs life
56
what triggers duct development
oestrogen
57
what trtiggers lobule formation
progesterone