reactions Flashcards
primary mediator of type I hypersensitivity reaction is _________
Immunoglobulin E (IgE)
most common allergies are type ____
I
allergy S&S -5
watery eyes, runny nose, sneezing, nasal congestion, itchy rash or hives
life-threatening allergic reaction; immediate type I hypersensitivity and rapid release of IgE
Anaphylaxis
Anaphylaxis S&S in lungs - 4
trouble breathing, coughing, sneezing, tightness in lungs
Anaphylaxis S&S in skin -4
pale skin, hives, itchy skin, sweating
Anaphylaxis S&S in the heart -4
chest pain, low BP, weak/rapid pulse, dizziness
Anaphylaxis S&S in the mouth -1
swelling of throat, face, lips, or tongue
Anaphylaxis S&S in the stomach -3
abdominal pain, nausea/vomiting, diarrhea
reactions are medicated by -
antigen-specific IgE and the products of tissue mast cell
what is a mast cell
plays a role in inflammation, helps defend against pathogens, and are involved in wound healing and tissue repair
mast cells are well-known for releasing ________
histamine
the first line of treatment with anaphylaxis
epinephrine
EPI-Pen dosage
0.3mg, one time use
epinephrine through SQ -3
onset- 5-10 mins
peak- 20 mins
duration- 1-4 hrs