RBC's Life cycle/Production Flashcards
How long do RBC’s live and why?
The RBC life span is about 120 days this is because of wear and tear.
This wear and tear affects the RBC’s plasma membrane when having to squeeze through small capillaries.
How are old RBC’s Excreted from the body?
They are removed by the spleen & liver. They get broken down by fixed phagocytic macrophages and the recycled products are used for many things such as building of new RBC’s.
What is the process called for the production of RBC’s?
It is referred to as “Erythropoiesis”.
Where does the RBC’s production start?
It starts in the Red bone marrow with a precursor cell called “pro-erythroblast”.
What are all the steps to RBC production (Erythropoiesis)?
1: In the red bone marrow a precursor cell called pro-erythroblast divides several times and begins producing cells that create Hemoglobin.
2: End the near of development the cell ejects the nucleus and becomes a “Reticulocyte”.
3: They pass from red bone marrow to the blood stream by squeezing through plasma membranes of adjacent endothelial cells of blood capillaries.
What is the first step to the Production of RBC’s?
In the red bone marrow a precursor cell called pro-erythroblast divides several times and begins producing cells that create Hemoglobin.
What is the second step to the Production of RBC’s?
End the near of development the cell ejects the nucleus and becomes a “Reticulocyte”.
What is the third step to the Production of RBC’s?
They pass from red bone marrow to the blood stream by squeezing through plasma membranes of adjacent endothelial cells of blood capillaries.
What is Hypoxia?
This is when to little oxygen is entering the tissues.
What is the main stimulus for Erythropoiesis?
It is Hypoxia at the tissue level.
