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Block 6 > RBC Disorder Matching > Flashcards

RBC Disorder Matching Flashcards

1
Q

shistocyte

A

microahgioathic hemolytic anemia

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2
Q

polychromasia

A

reticulocytosis

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3
Q

band neutrophil

A

infection

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4
Q

basophilic stippling

A

lead poisoning

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5
Q

acanthocyes

A

liver disease

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6
Q

dole bodies

A

infection

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7
Q

Howell Jolly body

A

splenectomy

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8
Q

Pelter-Huet cell

A

myelodysplastic synddromes

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9
Q

rouleau

A

plasma cell myeloma

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10
Q

red cell agglutinates

A

cold agglutinin disease

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11
Q

spherocytes

A

autoimmune hemolytic anemia

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12
Q

hypochromia

A

iron deficiency anemia

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13
Q

macrocytosis

A

B12 deficiency

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14
Q

neutrophil hyperlobation

A

B12 deficiency

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15
Q

paroxysmal nocturnal hemoglobinuria

A

clonal disorder of PIG-A gene making RBCs sensitive to complement mediated lysis

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16
Q

sickle cell disease

A

point mutation resulting in abnormal hemoglobin and reduced RBC survivial

17
Q

thalassemia major

A

genetic disorder causing reduced synthesis of global chains

18
Q

warm autoimmune hemolytic anemia

A

production of RBC autoantibody causing extravascular hemolysis at body temperature

19
Q

cold agglutinin syndrome

A

production of RBC autoantibody on exposure to mycoplasma pneumoniae or EBV

20
Q

paroxysmal cold hemoglobinuria

A

autoimmune hemolytic disorder associated with IgG biphasic hemolysin

21
Q

hereditary spherocytosis

A

autosomal dominant genetic defect in ankyrin causing RBC membrane fragility

22
Q

aplastic crisis

A

red cell aplasia induced by parvovirus B19 infection

23
Q

G6PD deficiency

A

X linked enzyme deficiency resulting in acute hemolysis on exposure to oxidative compounds

24
Q

immune thrombocytopenia purpura

A

autoantibody coats patient’s platelets causing removal from circulation

25
Q

neonatal alloimmune thrombocytopenia

A

alloantibody coats patient’s platelets causing destruction

26
Q

heparin induced thrombocytopenia

A

antibody against heparin-PF4 complex leading to thrombocytopenia and thrombosis

27
Q

thrombotic thrombocytopenia purpura

A

autoantibody against ADAMTS13 leading to thrombocytopenia and MAHA

28
Q

Glanzmann thrombobasthenia

A

Genetic lack of GP2b3a platelet receptor for vWF

29
Q

bernard Soulier syndrome

A

genetic lack of GP1b platelet receptor for fibrinogen

30
Q

von Willebrand disease

A

platelet function defect where platelets do not normally bind to injured endothelium through the GP1b receptor

31
Q

Hemophilia B

A

genetic deficiency of factor 9 production

32
Q

disseminated intravascular coagulation

A

coagulopathy associated with abnormal bleeding and clotting

Block 6 (24 decks)

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