Random and Extra IDR

Question 1

What is Chlorpropamide, tolbutamide, and tolazamide responsible for?

Answer 1

Sulfonylureas

Question 2

What transcription factor do Thiazolidinediones increase?

Answer 2

PPAR-gamma, decrease insulin resistance

Question 3

What do fibrates increase?

Answer 3

LPL, increase triglyceride clearance, and PPAR-alpha, best at lowering triglycerides

Question 4

What does niacin decrease?

What is niacin’s big long term effect?

Answer 4

inhibit A-1 breakdown

acanthosis nigricans, gout too

Question 5

When something is cytokeratin and calretinin positive, what am I most likely?

Answer 5

Mesothelioma, psammoma bodies on histology

Question 6

What drug will not work when the patient is on theophylline?

Answer 6

adenosine

Question 7

Roflumilast is what kind of drug?

What disease is this found in?

Answer 7

phosphodiesterase inhibitor 4, decrease inflammation

COPD

Question 8

If I have diarrhea, pneumonia, and hyponatremia, what am I?

Answer 8

Legionella

Question 9

What drug is a recombinant form of uricase? not in skethy

Answer 9

rasburicase, treats hyperuricemia, and malignancy

Question 10

What drug, besides allopurinol inhibits xanthine oxidase, treats hyperuicemia?

Answer 10

Febuxostat, we are not in sketchy

Question 11

What is pegloticase MOA?

Answer 11

convert uric acid to allantoin, treat chronic gout, this is “Holy water to go” in Catholic Church Sketchy

Question 12

What is hemostatsis thing is Vasopressin attached too?

Answer 12

factor VIII

Question 13

What is in the striatum?

What is in the Lentiform?

Answer 13

putamen and caudate

putamen and globus pallidus

Question 14

ARDS vs CHF, both xrays look awful, what is the best overall test to use or to have?

Answer 14

PCPW will be normal, despite an xray that looks like the picture provided

Question 15

Flucytosine inhibits DNA and RNA synthesis via by what enzyme blockage?

Answer 15

cytosine deaminase

Question 16

What two drugs are used in an emergency for malaria?

Answer 16

Quinidine or artesunate

Question 17

In P vivax, what am I supposed to give in order to stop hypnozoites in the liver?

Answer 17

primaquine

Question 18

What are the two drugs used for organophosphate poisoning?

Answer 18

atropine and pralidoxime

Question 19

Neostigmine, physostigimine, and pyridostigmine all increase Ach in one way or another, which one crosses the CNS?

Answer 19

Physostigmine

Question 20

What is used in autonomic insufficiency and postural hypotension, may make supine hypertension, alpha 1 agonist?

Answer 20

Midodrine

Question 21

Makonkey agar there is growth, but no color, it means what? Mackonkey agar there is growth and it is pink, what is it?

Answer 21

no color = no lactose fermentation pink color = lactose fermentation

Question 22

In the world of bacteria, chlamydia does not make what?

Answer 22

muramic acid is not made

Question 23

Mycobacteria need what special stain?

Answer 23

Ziehl-Neelsen

Question 24

Gram negative bacteria have Lipid A and o-polysaccharide. O-polysccharide is the main target of what man made thing?

Answer 24

Antibiotics

Question 25

Spores have three layers, what is the innermost layer?

Answer 25

Dipicolnic acid

Question 26

What drug, not in sketchy, psych topic, inhibits serotonin reuptake, receptor partial agonist, used for MDD?

Answer 26

Vilazodone

Question 27

What psych drug inhibits 5-HT reuptake, 5-HT1a receptor agonist and 5HT3 antagonist, used for MDD?

Answer 27

Vortioxetine

Question 28

What type of immunity does Live attenuated vaccine keep up?

Answer 28

Cell Mediated and Humoral Response

Question 29

What is the vaccine? Clostridium tetani Corynebacterium diphtheriae

Answer 29

Toxoid Vaccine

Question 30

What does the killed or inactivated vaccine stimulate the immune system?

Answer 30

Humoral Response

Question 31

Tick vector mulberry like inclusions Monocytes with a morulae what disease is this?

Answer 31

Ehrlichiosis

Question 32

Tick vector granulocytes morulae in cytoplasm what disease is this?

Answer 32

Anaplasmosis

Question 35

Heat labile E. Coli toxin has an increase in what? Heat Stable E. Coli toxin has an increase in what?

Answer 35

increase cAMP, increase Cl and H20 in gut increase cGMP, decrease Cl NaCl and H20 in gut

Question 36

What things are in the Thayer-Martin Agar? Name 4

Answer 36

Trimethoprim Colistin Nystatin Vancomycin

Question 37

What does Sabouraud agar stain for?

Answer 37

Fungi

Question 38

What kind of mosquito helps with Dengue fever?

Answer 38

Aedes

Question 39

What is eosinophillic intranuclear inclusions?

Answer 39

Herpes Simplex virus

Question 40

What are basophilic intracytoplasmic inclusions?

Answer 40

Chylamdia Trachomatosis

Question 41

Eosinophillic intracytoplasmic inclusions are what?

Answer 41

Pox Virus or Rhabdo virus

Question 42

What is bipolar staining intracytoplasmic inclusions?

Answer 42

Klebsiella Granulomatosis or Donovan Bodies