Random and Extra IDR Flashcards
What is Chlorpropamide, tolbutamide, and tolazamide responsible for?
Sulfonylureas
What transcription factor do Thiazolidinediones increase?
PPAR-gamma, decrease insulin resistance
What do fibrates increase?
LPL, increase triglyceride clearance, and PPAR-alpha, best at lowering triglycerides
What does niacin decrease?
What is niacin’s big long term effect?
inhibit A-1 breakdown
acanthosis nigricans, gout too
When something is cytokeratin and calretinin positive, what am I most likely?
Mesothelioma, psammoma bodies on histology
What drug will not work when the patient is on theophylline?
adenosine
Roflumilast is what kind of drug?
What disease is this found in?
phosphodiesterase inhibitor 4, decrease inflammation
COPD
If I have diarrhea, pneumonia, and hyponatremia, what am I?
Legionella
What drug is a recombinant form of uricase? not in skethy
rasburicase, treats hyperuricemia, and malignancy
What drug, besides allopurinol inhibits xanthine oxidase, treats hyperuicemia?
Febuxostat, we are not in sketchy
What is pegloticase MOA?
convert uric acid to allantoin, treat chronic gout, this is “Holy water to go” in Catholic Church Sketchy
What is hemostatsis thing is Vasopressin attached too?
factor VIII
What is in the striatum?
What is in the Lentiform?
putamen and caudate
putamen and globus pallidus
ARDS vs CHF, both xrays look awful, what is the best overall test to use or to have?
PCPW will be normal, despite an xray that looks like the picture provided
Flucytosine inhibits DNA and RNA synthesis via by what enzyme blockage?
cytosine deaminase
What two drugs are used in an emergency for malaria?
Quinidine or artesunate
In P vivax, what am I supposed to give in order to stop hypnozoites in the liver?
primaquine
What are the two drugs used for organophosphate poisoning?
atropine and pralidoxime
Neostigmine, physostigimine, and pyridostigmine all increase Ach in one way or another, which one crosses the CNS?
Physostigmine
What is used in autonomic insufficiency and postural hypotension, may make supine hypertension, alpha 1 agonist?
Midodrine
Makonkey agar there is growth, but no color, it means what? Mackonkey agar there is growth and it is pink, what is it?
no color = no lactose fermentation pink color = lactose fermentation
In the world of bacteria, chlamydia does not make what?
muramic acid is not made
Mycobacteria need what special stain?
Ziehl-Neelsen
Gram negative bacteria have Lipid A and o-polysaccharide. O-polysccharide is the main target of what man made thing?
Antibiotics
Spores have three layers, what is the innermost layer?
Dipicolnic acid
What drug, not in sketchy, psych topic, inhibits serotonin reuptake, receptor partial agonist, used for MDD?
Vilazodone
What psych drug inhibits 5-HT reuptake, 5-HT1a receptor agonist and 5HT3 antagonist, used for MDD?
Vortioxetine
What type of immunity does Live attenuated vaccine keep up?
Cell Mediated and Humoral Response
What is the vaccine?
Clostridium tetani
Corynebacterium diphtheriae
Toxoid Vaccine
What does the killed or inactivated vaccine stimulate the immune system?
Humoral Response
Tick vector
mulberry like inclusions
Monocytes with a morulae
what disease is this?
Ehrlichiosis
Tick vector
granulocytes
morulae in cytoplasm
what disease is this?
Anaplasmosis
Heat labile E. Coli toxin has an increase in what?
Heat Stable E. Coli toxin has an increase in what?
increase cAMP, increase Cl and H20 in gut
increase cGMP, decrease Cl NaCl and H20 in gut
What things are in the Thayer-Martin Agar?
Name 4
Trimethoprim
Colistin
Nystatin
Vancomycin
What does Sabouraud agar stain for?
Fungi
What kind of mosquito helps with Dengue fever?
Aedes
What is eosinophillic intranuclear inclusions?
Herpes Simplex virus
What are basophilic intracytoplasmic inclusions?
Chylamdia Trachomatosis
Eosinophillic intracytoplasmic inclusions are what?
Pox Virus or Rhabdo virus
What is bipolar staining intracytoplasmic inclusions?
Klebsiella Granulomatosis or Donovan Bodies
