Random and Extra IDR Flashcards
What is Chlorpropamide, tolbutamide, and tolazamide responsible for?
Sulfonylureas
What transcription factor do Thiazolidinediones increase?
PPAR-gamma, decrease insulin resistance
What do fibrates increase?
LPL, increase triglyceride clearance, and PPAR-alpha, best at lowering triglycerides
What does niacin decrease?
What is niacin’s big long term effect?
inhibit A-1 breakdown
acanthosis nigricans, gout too
When something is cytokeratin and calretinin positive, what am I most likely?
Mesothelioma, psammoma bodies on histology
What drug will not work when the patient is on theophylline?
adenosine
Roflumilast is what kind of drug?
What disease is this found in?
phosphodiesterase inhibitor 4, decrease inflammation
COPD
If I have diarrhea, pneumonia, and hyponatremia, what am I?
Legionella
What drug is a recombinant form of uricase? not in skethy
rasburicase, treats hyperuricemia, and malignancy
What drug, besides allopurinol inhibits xanthine oxidase, treats hyperuicemia?
Febuxostat, we are not in sketchy
What is pegloticase MOA?
convert uric acid to allantoin, treat chronic gout, this is “Holy water to go” in Catholic Church Sketchy
What is hemostatsis thing is Vasopressin attached too?
factor VIII
What is in the striatum?
What is in the Lentiform?
putamen and caudate
putamen and globus pallidus
ARDS vs CHF, both xrays look awful, what is the best overall test to use or to have?
PCPW will be normal, despite an xray that looks like the picture provided
Flucytosine inhibits DNA and RNA synthesis via by what enzyme blockage?
cytosine deaminase
What two drugs are used in an emergency for malaria?
Quinidine or artesunate