Random and Extra IDR Flashcards

1
Q

What is Chlorpropamide, tolbutamide, and tolazamide responsible for?

A

Sulfonylureas

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2
Q

What transcription factor do Thiazolidinediones increase?

A

PPAR-gamma, decrease insulin resistance

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3
Q

What do fibrates increase?

A

LPL, increase triglyceride clearance, and PPAR-alpha, best at lowering triglycerides

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4
Q

What does niacin decrease?

What is niacin’s big long term effect?

A

inhibit A-1 breakdown

acanthosis nigricans, gout too

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5
Q

When something is cytokeratin and calretinin positive, what am I most likely?

A

Mesothelioma, psammoma bodies on histology

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6
Q

What drug will not work when the patient is on theophylline?

A

adenosine

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7
Q

Roflumilast is what kind of drug?

What disease is this found in?

A

phosphodiesterase inhibitor 4, decrease inflammation

COPD

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8
Q

If I have diarrhea, pneumonia, and hyponatremia, what am I?

A

Legionella

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9
Q

What drug is a recombinant form of uricase? not in skethy

A

rasburicase, treats hyperuricemia, and malignancy

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10
Q

What drug, besides allopurinol inhibits xanthine oxidase, treats hyperuicemia?

A

Febuxostat, we are not in sketchy

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11
Q

What is pegloticase MOA?

A

convert uric acid to allantoin, treat chronic gout, this is “Holy water to go” in Catholic Church Sketchy

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12
Q

What is hemostatsis thing is Vasopressin attached too?

A

factor VIII

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13
Q

What is in the striatum?

What is in the Lentiform?

A

putamen and caudate

putamen and globus pallidus

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14
Q

ARDS vs CHF, both xrays look awful, what is the best overall test to use or to have?

A

PCPW will be normal, despite an xray that looks like the picture provided

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15
Q

Flucytosine inhibits DNA and RNA synthesis via by what enzyme blockage?

A

cytosine deaminase

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16
Q

What two drugs are used in an emergency for malaria?

A

Quinidine or artesunate

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17
Q

In P vivax, what am I supposed to give in order to stop hypnozoites in the liver?

A

primaquine

18
Q

What are the two drugs used for organophosphate poisoning?

A

atropine and pralidoxime

19
Q

Neostigmine, physostigimine, and pyridostigmine all increase Ach in one way or another, which one crosses the CNS?

A

Physostigmine

20
Q

What is used in autonomic insufficiency and postural hypotension, may make supine hypertension, alpha 1 agonist?

A

Midodrine

21
Q

Makonkey agar there is growth, but no color, it means what? Mackonkey agar there is growth and it is pink, what is it?

A

no color = no lactose fermentation pink color = lactose fermentation

22
Q

In the world of bacteria, chlamydia does not make what?

A

muramic acid is not made

23
Q

Mycobacteria need what special stain?

A

Ziehl-Neelsen

24
Q

Gram negative bacteria have Lipid A and o-polysaccharide. O-polysccharide is the main target of what man made thing?

A

Antibiotics

25
Q

Spores have three layers, what is the innermost layer?

A

Dipicolnic acid

26
Q

What drug, not in sketchy, psych topic, inhibits serotonin reuptake, receptor partial agonist, used for MDD?

A

Vilazodone

27
Q

What psych drug inhibits 5-HT reuptake, 5-HT1a receptor agonist and 5HT3 antagonist, used for MDD?

A

Vortioxetine

28
Q

What type of immunity does Live attenuated vaccine keep up?

A

Cell Mediated and Humoral Response

29
Q

What is the vaccine?

Clostridium tetani

Corynebacterium diphtheriae

A

Toxoid Vaccine

30
Q

What does the killed or inactivated vaccine stimulate the immune system?

A

Humoral Response

31
Q

Tick vector

mulberry like inclusions

Monocytes with a morulae

what disease is this?

A

Ehrlichiosis

32
Q

Tick vector

granulocytes

morulae in cytoplasm

what disease is this?

A

Anaplasmosis

35
Q

Heat labile E. Coli toxin has an increase in what?

Heat Stable E. Coli toxin has an increase in what?

A

increase cAMP, increase Cl and H20 in gut

increase cGMP, decrease Cl NaCl and H20 in gut

36
Q

What things are in the Thayer-Martin Agar?

Name 4

A

Trimethoprim

Colistin

Nystatin

Vancomycin

37
Q

What does Sabouraud agar stain for?

A

Fungi

38
Q

What kind of mosquito helps with Dengue fever?

A

Aedes

39
Q

What is eosinophillic intranuclear inclusions?

A

Herpes Simplex virus

40
Q

What are basophilic intracytoplasmic inclusions?

A

Chylamdia Trachomatosis

41
Q

Eosinophillic intracytoplasmic inclusions are what?

A

Pox Virus or Rhabdo virus

42
Q

What is bipolar staining intracytoplasmic inclusions?

A

Klebsiella Granulomatosis or Donovan Bodies