Odd stuff

Question 1

What is the extrinsic pathway mechanism for apoptosis? What is the intrinsic pathway mechanism for apoptosis?

Answer 1

caspase 8 caspase 9, cytochrome c

Question 2

What bundle of joy has the Maltese cross? What are we really similar too, the same tick carries this too?

Answer 2

Babesiosis Lyme Disease

Question 3

What are the two terms: REduce the pathogenic organism counts to a safe level? Inactivate all microbes including spores?

Answer 3

Disinfect Sterilize

Question 4

What type of equipment does the following? Pressurized steam at 120 degrees C, sporicidal, may not reliably inactivate prions

Answer 4

Autoclave

Question 5

What type of equipment does the following? Denature proteins and disrupt cell membranes, not sporicidal Name 2

Answer 5

Alcohols and Chlorhexidine

Question 6

What type of equipment does the following? Oxidizes and denatures proteins, sporicidal

Answer 6

Chlorine

Question 7

What type of equipment does the following? Alkylating agent, sporicidial

Answer 7

Ethylene oxide

Question 8

What type of equipment does the following? Free radical oxidation, sporicidal

Answer 8

Hydrogen Peroxide

Question 9

What type of equipment does the following? Halogenation of DNA and RNA, and proteins, may not be sporicidal

Answer 9

Iodine and Iodophors

Question 10

What type of equipment does the following? Impair permeability of cell membranes, not sporicidal

Answer 10

Quaternary Amines

Question 11

What disease is mixed cryoglobulinemia associated with? Palpable purpura, weakness, arthralgias

Answer 11

Hep C

Question 12

Von Hippel-Lindau disease Renal Cell Carcinoma What is the magic chromosome?

Answer 12

Chromosome 3

Question 13

ADPKD (PKD2), achondroplasia Huntington Disease What is the magic chromosome?

Answer 13

Chromosome 4

Question 14

Cri-du-chat syndrome Familial adenomatous polyposis (FAP) What is the magic chromosome?

Answer 14

Chromosome 5

Question 15

Hemochromatosis (HFE) What is the magic chromosome?

Answer 15

Chromosome 6

Question 16

Friedreich ataxia Tuberous Sclerosis (TSC1) What is the magic chromosome?

Answer 16

Chromosome 9

Question 17

Wilms Tumor B globin defects (sickle cell disease, B-Thalassemia) MEN 1 What is the magic chromosome?

Answer 17

Chromosome 11

Question 18

Patau Syndrome Wilson Disease Retinoblastoma BRCA2 What is the magic chromosome?

Answer 18

Chromosome 13

Question 19

Prader-Willi Syndrome Angelman Syndrome Marfan Syndrome What is the magic chromosome?

Answer 19

Chromosome 15

Question 20

ADPKD (PKD1) Alpha globin gene defects (alpha thalassemia) Tuberous Sclerosis (TSC2) What is the magic chromosome?

Answer 20

Chromosome 16

Question 21

Neurofibromatosis type 1 BRCA1 TP53 What is the magic chromosome?

Answer 21

Chromosome 17

Question 22

Edwards Syndrome What is the magic chromosome?

Answer 22

Chromosome 18

Question 23

Down Syndrome What is the magic chromosome?

Answer 23

Chromosome 21

Question 24

Neurofibromatosis Type 2, DiGeorge Syndrome What is the magic chromosome?

Answer 24

Chromosome 22

Question 25

Fragile X X-linked agammaglobulinemia Klinefelter Syndrome (XXY) What is the magic chromosome?

Answer 25

Chromosome X

Question 26

Digoxin binds to the Na/K pump What drug binds to the K channels, with the same intention as Digoxin?

Answer 26

Ouabain

Question 27

Williams Syndrome Cystic Fibrosis What is the magic chromosome?

Answer 27

Chromosome 7

Question 28

What is different mutations in the same locus produce the same phenotype?

Answer 28

Allelic Heterogeneity Beta Thalassemia

Question 29

What is the -ximab used for/from? i.e. Rituximab

Answer 29

Chimeric human-mouse monoclonal AB

Question 30

What is the -zumab used for/from? i.e. Bevacizumab

Answer 30

Humanized mouse monoclonal AB

Question 31

What is the -umab used for/from? i.e. Denosumab

Answer 31

Human monoclonal AB

Question 32

What is the -tinib used for/from?

Answer 32

Tyrosine kinase inhibitor

Question 33

What is the -zomib used for/from?

Answer 33

Proteasome inhibitor

Question 34

What is the -ciclib used for/from?

Answer 34

Cyclin-dependent kinase inhibitor

Question 35

What is the -cept ending used for?

Answer 35

TNF-alpha antagonist

Question 36

What is the -leukin used for?

Answer 36

Aldesleukin

Question 37

What is the -kinra used for?

Answer 37

Interleukin receptor Antagonist

Question 38

What does Adalimumab, certolizumab, golimumab, and infliximab go after?

Answer 38

TNF-alpha

Question 39

What does Daclizumab target?

Answer 39

CD25, used in M.S.

Question 40

What does Eculizumab target?

Answer 40

Complement protein C5

Question 41

What does Natalizumab target?

Answer 41

alpha-4- integrin

Question 42

What does Ustekinumab target?

Answer 42

IL-12/IL-23

Question 43

What does Abciximab target?

Answer 43

Platelet glycoproteins IIb/IIIa

Question 44

What does Denosumab target?

Answer 44

RANKL, this is the dinosaur holding the hand crank drill in sketchy

Question 45

What does Omalizumab target?

Answer 45

IgE, this is the limo in the parade anti-inflammatory sketchy

Question 46

What does Palivizumab target?

Answer 46

RSV F Protein

Question 47

What is Erlotinib used for?

Answer 47

EGFR tyrosine Kinase inhibitor, “Geoffery, British Earl” Non small cell lung carcinoma

Question 48

What is cetuximab used for?

Answer 48

antibody against EGFR, colon cancer, tux from the elephant in sketchy

Question 49

What is Imatinib used for?

Answer 49

Tyrosine kinase BCR-ABL, inhibitor, Philly chromosome, CML “broken bell”, “Imitation guy in sketchy”