Radiotherapy And Hormonal Therapy In Breast Cancer

Question 1

Radiotherapy indications

Answer 1

+ve lymph nodes
Tumour more than 5 CM
After breast conservative surgey
Locally advanced breast cancer (LABC)

Question 2

RADIOTHERAPY TYPES

Answer 2

Whole breast irradiation(25 days) (50-55 gy) (one fraction/day)

Accelerated partial breast irradiation(5days) 30-35gy(2 sitting per day)

Question 3

Brachytherapy

Answer 3

Electrodes put into tumour cavity snd radiation goes to tumour bed

Question 4

Accelerated partial breast irradiation indications

Answer 4

> 50 yrs
T1
Node negative
ER, PR +ve
Unifocal
No lymphovascular invasion

Question 5

Hormonal therapy is only for

Answer 5

ER, PR positive

Question 6

Hormonal therapy for pre menopausal patient

Answer 6

SERM(Tamoxifen)

Traditionally 5 years
Now 10 years

SE- HOT FLASHES(mc)
Deep venous thrombosis
Endometroal hyperplasia

Question 7

Hormone therapy for post menopausal women

Answer 7

Aromatase inhibitors

ANASTROZOLE
LETROZOLE
EXIMASTINE

5-10 YEARS (Osteoporosis)