Molecular Classification Of Breast Cancer Flashcards
1
Q
Three receptors in gene expression profiling
A
ER
PR
HER 2 NEU
Ki 67
2
Q
Alred score ranges from
A
0-8
ER PR
3
Q
Negative staining for HER2NEU
A
0,+1
4
Q
Equivocal for HER2NEU
A
+2
5
Q
Postive HER2NEU Score
A
3+
6
Q
FISH
A
Fluorescent insitu hybridization
7
Q
Proliferation index marker
A
Ki67
8
Q
High incidence of visceral metastasis
A
Triple negative
9
Q
TNBC paradox
A
Show good response
Relapse after 1 n half - 2 years
Cytokeratin 5,6 positive
10
Q
New updates in breast cancer
A
Isolated tumour cells(ITC)
<=0.2mm cluster or 200 cells
Micrometastasis
>0.2mm<=2mm
Or cluster of 200 cells
11
Q
First draining lymph node from breast cancer
A
Sentinal LN
12
Q
If sentinal LN has isolated tumour cells or micretastasis
A
Consider Negative and no LN removal
No radiotherapy
