Focal Nodular Hyperplasia And Liver Adenoma Flashcards

1
Q

2nd most benign tumour of liver

A

Focal nodular hyperplasia

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2
Q

Fodular nodular hyperplasia may be secondary to

A

Secondary vascular insult to liver

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3
Q

Histopathology of focal nodular hyperplasia

A

Hepactocytes
Bile duct structure
Kupffer cells
Hot spot on tc99 sulphur colloid scanning

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4
Q

Hot spot on tc99 sulphur colloid scan on focal nodular hyperplasia is due to

A

Kupffer cells

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5
Q

Clinical features

A

Asymptomatic
Incidental

Ioc CECT

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6
Q

CECT finding in FNH

A

Central stellate scar

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7
Q

Central stellate scar is seen in

A

FNH
chromophobe RCC
Oncocytoma

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8
Q

Managent of FNH

A

Observation

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9
Q

Hepatic adenpma is common in

A

Females

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10
Q

Liver cancer that has strongest association with OCP is

A

Hepatic adenoma

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11
Q

Histopathology

A

Sheets of hepatocytes
No bile duct structures
No kupffer cells

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12
Q

How many percent patient with liver adenoma show malignant conversion

A

10%

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13
Q

Spontaneous rupture of hepatic adenoma can cause

A

Non traumatic haemoperitoneum

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14
Q

IOC

A

CECT

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15
Q

Management of liver adenoma

A

All liver adenoma has to resected becoz risk of malignant conversion

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16
Q

Bordeaux classification for liver adenoma

A

Inflammatory liver adenoma ( max risk of bleeding)
HNF1 alpha mutated ( multiple and in young)
Beta- catenin mutation ( max risk of malignant conversion)

17
Q

Malebpatoents on anabolic steroids having liver adenoma has what mutation

A

Beta-catenin mutation

18
Q

Multiple liver hamartoma sx also called

A

Von meinberg diseases
(Multiple cystic liver hamartomas)

19
Q

Von meinbergs disease is due to

A

Failure of regression of embryonic biliary duct

20
Q

CF of von meinbergs disease

A

Asymptomatic

21
Q

Multiple liver hamartoma patient has increased risk of

A

Cholangiocarcinoma

Aslo association with PCKD

22
Q

Multiple cabernous hemangiomas in liver is called

A

Pelipsis hepatis

23
Q

Peliosis hepatis is seen in

A

Immunocompromised patients
Anabolic steroids