Medullary Thyroid Cancer Flashcards by Nishanth Murugan | Brainscape

Q

Arises from

A

Parafollicular cells(C-cells)

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Q

Familial medullary thyroid cancer

A

MEN 2 SX
MEN 2B SX
Younger age
Multicentric

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Q

Diagnosis

A

Pentagastrin stimulation

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Q

Clinical features

A

Thyroid swelling
Diarrhoea
Flushing
Cushing

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Q

Lymphatic spread

A

Level 6 lymph node

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Q

Anaplastic thyroid carcinoma Hematogenous spread

A

Liver

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Q

Diagnostic finding

A

FNAC

Amyloid rich stroma

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Q

Management

A

One step ahead surgery

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Q

FDA approved for metastaticTC

A

Vandetinib
Carbozantinib

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Q

What should you ruleout before surgery in MTC

A

Pheochromocytoma

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