Anaplastic Thyroid Carcinoma And Thyroid Lymphoma Flashcards
1
Q
Genetics
A
P53 mutation
MiRNA 17-92 Upregulated
Beta catenin mutations
2
Q
Long standing goitre rapidly increasing in size
A
Follicular thyroid cancer
3
Q
Rapidly increasing thyroid swelling
A
Anaplastic
4
Q
Local invasions of ATC
A
RLN-hoarseness of voice
Trachea-stidor Or dyspnea
Very hard thyroid swelling
5
Q
Distant metastasis of PTC and ATC
A
Lungs
6
Q
Tru-cut biopsy indication
A
FNAC inconclusive in ATC
Reidels thyroiditis
7
Q
Aggressive surgery
A
Restricted to thyroid
(TT+CND+MRND)
8
Q
Beyond thyroid
A
Palliative
9
Q
Drug for Metastatoc ATC
A
Dabrafenib
10
Q
If pressure over trachea in ATC
A
Isthumectomy
11
Q
Type
A
Non hodgkins B-Cell lymphoma
(Diffuse or small blue cell tumour)
12
Q
B symptoms
A
Fever
Night sweats
wt loss
13
Q
Management
A
Rituximab
Cyclophospamide
Hydroxy danorubesin
Oncovin
Prednisolone
+ rt
14
Q
If residual or recurrent
A
Surgery
