RA Flashcards
1
Q
What is the most common pro-inflammatory substances associated with RA?
A
Tumor necrosis factor (TNF), IL-1, & IL-6
2
Q
What should you give for GI bleeding?
A
PPIs
3
Q
What are mostly used with RA?
A
DMARDs
4
Q
What is the preferred & most commonly used traditional DMARD, inhibits the Dihydrofolic acid reductase enzyme, and Delayed drug clearance is one of the major factors responsible for toxicity?
A
Methotrexate
5
Q
What is a Janus kinase (JAK) inhibitor & synthetic, suppresses immune cell function. It’s not a first-line agent and is not recommended for pts w/ early RA?
A
Tofacitinib
6
Q
What is the Black box warning of Tofacitinib?
A
lymphomas & other cancers
