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Meharry Biochem > Quiz 3 > Flashcards

Quiz 3 Flashcards

1
Q

bile pigments are formed in…

A

the degredation of heme

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2
Q

which following enzymes is not involved in the assimilaiton of inorganic nitrogen into an organic molecule

A

nitrile reductase

arginase

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3
Q

which substrate is not involved in the production of urea from NH4 via the urea cycle

A

malate

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4
Q

nitrogen fixation by the dinitrogenase complex produces what gas

A

produces NH3 and H2 gas

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5
Q

siroheme is a heme like prosthetic group used by some enzymes to accomplish the 6 electron reduction of sulfur to nitrogen . it is part of the —- complex

A

nitrite reductase?, plays a role in the assimilation pathway

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6
Q

non essential amino acids

A

PVT TIM HALL
phenylalanine, valine, threonine
tryptophan , isoleucine , methionine
histidine, arginine, leucine lysine

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7
Q

histidine synthesis use which pair of molecules early in the pathway

A

comes from ribose 5 phosphate. uses purine ring of ATP and gln as source of N

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8
Q

an amino acid that does not derive its carbon skeleton at least in part from alpha keto glutarate is

A

anything except for glutamate, glutamate proline or arginine

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9
Q

the enzymatic machinary to fix atmospheric nitrogen into nh4 is

A

nitrogenase complex. Has 2 Subunits: Dinitrogenase Reductase and dinitrogenase

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10
Q

vitamin e functions as an antioxidant and protects poly unsaturated fates from peroxidation which of the following is the active from of vitamin E

A

alpha tocopherol

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11
Q

which of the follwing enzymes is a feeder for the urea cycle

A

carbomyl phosphate synthetase 1

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12
Q

the liquid separated out and placed into a blood tube is

A

? liquid After clotting = Serum

liquid Before clotting = Plasma

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13
Q

the intake of which of the follwing amino acids is need to prevent microtic anemia

A

?

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14
Q

which of the following is the correct order for the steps involved in hemostasis

A
  1. Injury on lining of blood vessel
  2. Platelets adhere to cut site
  3. platelets secrete things for vasoconstriction
  4. Thrombin generated
  5. fibrin clot formed
  6. clot lysis - wound healing
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15
Q

which is released from a damaged tissue to initiate a chain of reactions leading to blood clotting

A

tissue factor –> thrombin–> fibrinogin –> cross linked

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16
Q

which of the following amino acids is used for heme biosynthesis in animals and higher eukaryotes

A

glycine and succinyl coa

17
Q

which of the following is not an intermeditate in glycolysis or gluconeogeneis in mammalian liver

A

fructose 2,6 bisphosphate

18
Q

the amino acid — is an intermediate in the biosnthesis of —

A

glycine , heme

19
Q

which one of the floowing amino acids is directly involved in the purine biosynthetic pathway

A

aspartate

20
Q

which of the follwoing combination acts a reserve to help maintain the immediate ATP adp ration in highly working muscles

A

creatine / phosphocreatine

21
Q 
Which of the following enzymes is NOT involved in the assimilation of inorganic nitrogen into an organic molecule? 
Arginase 
Glutamate dehydrogenase 
Glutamate synthase 
Glutamine synthetase 
Nitrogenase
A

Arginase

22
Q 
Erythrose 4-phosphate is a precursor of: 
aspartate. 
cysteine. 
phenylalanine. 
serine. 
threonine.
A

phenylalanine

23
Q

Glutamine synthetase converts ___ to ___ whereas glutamate synthase converts __to___.

Formate; glutamine;
ammonia; glutamate

Asparagine; glutamine;
alpha-ketoglutarate;
glutamate

alpha-ketoglutarate;
glutamine; oxaloacetic acid;
glutamate

alpha-ketoglutarate; glutamine; alpha-ketoglutarate; glutamate

glutamate; glutamine; alpha-ketoglutarate; glutamate

A

glutamate; glutamine; alpha-ketoglutarate; glutamate

24
Q

Which of the following statements about the fixation of atmospheric nitrogen (N2) into NH3 by living cells is FALSE?

It involves the transfer of 8 electrons per mol of N2.

It occurs in certain microorganisms, but not in humans.
It requires a source of electrons, normally ferredoxin.

It requires one ATP per mol of N2 fixed.

It requires two key protein components, each containing iron.

A

It requires one ATP per mol of N2 fixed.

25
Q

Which substance is NOT involved in the production of urea from NH4+ via the urea cycle?

A 
Aspartate 
ATP
Carbamoyl phosphate 
Malate 
Ornithine
26
Q

The coenzyme involved in a transaminase reaction is:

biotin phosphate.

lipoic acid.

nicotinamide adenine dinucleotide phosphate (NADP+).

pyridoxal phosphate (PLP).

thiamine pyrophosphate (TPP).

A

pyridoxal phosphate (PLP).

27
Q

The human genetic disease phenylketonuria (PKU) can result from:

deficiency of protein in the diet.
inability to catabolize ketone bodies.

inability to convert phenylalanine to tyrosine.

inability to synthesize phenylalanine.

production of enzymes containing no phenylalanine.

A

inability to convert phenylalanine to tyrosine.

28
Q

Nonessential amino acids:

are amino acids other than those required for protein synthesis.

are not utilized in mammalian proteins.

are synthesized by plants and bacteria, but not by humans.

can be synthesized in humans as well as in bacteria.

may be substituted with other amino acids in proteins.

A

can be synthesized in humans as well as in bacteria.

29
Q

Which of the following is NOT true about the anammox reaction?

Anammox converts ammonia to nitrogen

Anammox id performed by symbiotic bacteria of leguminous plants

Anammox generates the highly reactive molecule hydrazine that is a component of rocket fuel

Anammox occurs anaerobically
The ultimate electron acceptor in anammox is nitrite

A

Anammox id performed by symbiotic bacteria of leguminous plants

30
Q

What does von Willebrand factor do?

Binds platelets to each other
Binds platelets to the sub endothelium

Binds platelets to the phospholipid surface

Carries factor VII

Cleaves factor V

A

Binds platelets to each other

Binds platelets to the sub endothelium

31
Q

Which of the following is TRUE about gout?

Gout is caused by excessive breakdown of pyrimidine nucleotides

Gout can be treated by administration of flurouracil

Gout is particularly prevalent in patients lacking xanthine oxidase

Gout lead to deposition of sodium urate crystals in the joints

Eating more liver is an effective way to treat the symptoms of gout

A

Gout lead to deposition of sodium urate crystals in the joints

32
Q

The ribosyl phosphate moiety needed for the synthesis of orotidylate, inosinate, and guanylate is provided most directly by:

5-phosphoribosyl 1-pyrophosphate.

adenosine 5’-phosphate.

guanosine 5’-phosphate.

ribose 5-phosphate.

ribulose 5-phosphate.

A

5-phosphoribosyl 1-pyrophosphate.

33
Q

Pyridoxal phosphate is required as a co-factor for which of the following?

Carboxylation of Acetyl-CoA

Transamination of amino acids

Carrier of methyl group

Methylation of homocysteine

None of the above

A

Transamination of amino acids

34
Q

Thrombin is _____
active enzyme

inactive enzyme

enxyme precursor

proenzyme

eoenzyme

A

active enzyme

35
Q

MP, UMP, and TMP all have ________________ as a common precursor.

adenosine
aspartate
glutamine
inosine
S-adenosyl methionine
A

aspartate

36
Q

Overconsumption of raw eggs results in deficiency of biotin. Raw egg whites contain__

Globulin
Avidin
Albumin
Lecithin
Aprotinin
A

Avidin

37
Q

Pantetheine derived from the vitamin Pantothrnic acid provides the prosthetic –SH group for__

NAD

Pyridoxamine

Acyl carrier protein

Hydroquinone

None of the above

A

Acyl carrier protein

38
Q

Vitamin E functions as an antioxidant and protects polyunsaturated fatty acids from perioxidation. Which…………

Alpha-tocopherol 
Cholecalciferol
11 cis-retinol
alpha-menadiol
riboflavinol
A

Alpha-tocopherol

39
Q

What is the correct order for clotting mechanism?

Thromboplastin, thrombin, prothrombin, fibrin, fibrinogen

Prothrombin, thromboplastin, thrombin, fibrin, fibrinogen

Fibrin, fibrinogen, thrombin, prothrombin, thromboplastin

Thromboplastin, prothrombin, thrombin, fibrinogen, fibrin

Fibrinogen, fibrin, thromboplastin, prothrombin, thrombin

A

Thromboplastin, prothrombin, thrombin, fibrinogen, fibrin

Meharry Biochem (17 decks)

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