Quiz 3 Flashcards
bile pigments are formed in…
the degredation of heme
which following enzymes is not involved in the assimilaiton of inorganic nitrogen into an organic molecule
nitrile reductase
arginase
which substrate is not involved in the production of urea from NH4 via the urea cycle
malate
nitrogen fixation by the dinitrogenase complex produces what gas
produces NH3 and H2 gas
siroheme is a heme like prosthetic group used by some enzymes to accomplish the 6 electron reduction of sulfur to nitrogen . it is part of the —- complex
nitrite reductase?, plays a role in the assimilation pathway
non essential amino acids
PVT TIM HALL
phenylalanine, valine, threonine
tryptophan , isoleucine , methionine
histidine, arginine, leucine lysine
histidine synthesis use which pair of molecules early in the pathway
comes from ribose 5 phosphate. uses purine ring of ATP and gln as source of N
an amino acid that does not derive its carbon skeleton at least in part from alpha keto glutarate is
anything except for glutamate, glutamate proline or arginine
the enzymatic machinary to fix atmospheric nitrogen into nh4 is
nitrogenase complex. Has 2 Subunits: Dinitrogenase Reductase and dinitrogenase
vitamin e functions as an antioxidant and protects poly unsaturated fates from peroxidation which of the following is the active from of vitamin E
alpha tocopherol
which of the follwing enzymes is a feeder for the urea cycle
carbomyl phosphate synthetase 1
the liquid separated out and placed into a blood tube is
? liquid After clotting = Serum
liquid Before clotting = Plasma
the intake of which of the follwing amino acids is need to prevent microtic anemia
?
which of the following is the correct order for the steps involved in hemostasis
- Injury on lining of blood vessel
- Platelets adhere to cut site
- platelets secrete things for vasoconstriction
- Thrombin generated
- fibrin clot formed
- clot lysis - wound healing
which is released from a damaged tissue to initiate a chain of reactions leading to blood clotting
tissue factor –> thrombin–> fibrinogin –> cross linked
which of the following amino acids is used for heme biosynthesis in animals and higher eukaryotes
glycine and succinyl coa
which of the following is not an intermeditate in glycolysis or gluconeogeneis in mammalian liver
fructose 2,6 bisphosphate
the amino acid — is an intermediate in the biosnthesis of —
glycine , heme
which one of the floowing amino acids is directly involved in the purine biosynthetic pathway
aspartate
which of the follwoing combination acts a reserve to help maintain the immediate ATP adp ration in highly working muscles
creatine / phosphocreatine
Which of the following enzymes is NOT involved in the assimilation of inorganic nitrogen into an organic molecule? Arginase Glutamate dehydrogenase Glutamate synthase Glutamine synthetase Nitrogenase
Arginase
Erythrose 4-phosphate is a precursor of: aspartate. cysteine. phenylalanine. serine. threonine.
phenylalanine
Glutamine synthetase converts ___ to ___ whereas glutamate synthase converts __to___.
Formate; glutamine;
ammonia; glutamate
Asparagine; glutamine;
alpha-ketoglutarate;
glutamate
alpha-ketoglutarate;
glutamine; oxaloacetic acid;
glutamate
alpha-ketoglutarate; glutamine; alpha-ketoglutarate; glutamate
glutamate; glutamine; alpha-ketoglutarate; glutamate
glutamate; glutamine; alpha-ketoglutarate; glutamate
Which of the following statements about the fixation of atmospheric nitrogen (N2) into NH3 by living cells is FALSE?
It involves the transfer of 8 electrons per mol of N2.
It occurs in certain microorganisms, but not in humans.
It requires a source of electrons, normally ferredoxin.
It requires one ATP per mol of N2 fixed.
It requires two key protein components, each containing iron.
It requires one ATP per mol of N2 fixed.
Which substance is NOT involved in the production of urea from NH4+ via the urea cycle?
Aspartate ATP Carbamoyl phosphate Malate Ornithine
The coenzyme involved in a transaminase reaction is:
biotin phosphate.
lipoic acid.
nicotinamide adenine dinucleotide phosphate (NADP+).
pyridoxal phosphate (PLP).
thiamine pyrophosphate (TPP).
pyridoxal phosphate (PLP).
The human genetic disease phenylketonuria (PKU) can result from:
deficiency of protein in the diet.
inability to catabolize ketone bodies.
inability to convert phenylalanine to tyrosine.
inability to synthesize phenylalanine.
production of enzymes containing no phenylalanine.
inability to convert phenylalanine to tyrosine.
Nonessential amino acids:
are amino acids other than those required for protein synthesis.
are not utilized in mammalian proteins.
are synthesized by plants and bacteria, but not by humans.
can be synthesized in humans as well as in bacteria.
may be substituted with other amino acids in proteins.
can be synthesized in humans as well as in bacteria.
Which of the following is NOT true about the anammox reaction?
Anammox converts ammonia to nitrogen
Anammox id performed by symbiotic bacteria of leguminous plants
Anammox generates the highly reactive molecule hydrazine that is a component of rocket fuel
Anammox occurs anaerobically
The ultimate electron acceptor in anammox is nitrite
Anammox id performed by symbiotic bacteria of leguminous plants
What does von Willebrand factor do?
Binds platelets to each other
Binds platelets to the sub endothelium
Binds platelets to the phospholipid surface
Carries factor VII
Cleaves factor V
Binds platelets to each other
Binds platelets to the sub endothelium
Which of the following is TRUE about gout?
Gout is caused by excessive breakdown of pyrimidine nucleotides
Gout can be treated by administration of flurouracil
Gout is particularly prevalent in patients lacking xanthine oxidase
Gout lead to deposition of sodium urate crystals in the joints
Eating more liver is an effective way to treat the symptoms of gout
Gout lead to deposition of sodium urate crystals in the joints
The ribosyl phosphate moiety needed for the synthesis of orotidylate, inosinate, and guanylate is provided most directly by:
5-phosphoribosyl 1-pyrophosphate.
adenosine 5’-phosphate.
guanosine 5’-phosphate.
ribose 5-phosphate.
ribulose 5-phosphate.
5-phosphoribosyl 1-pyrophosphate.
Pyridoxal phosphate is required as a co-factor for which of the following?
Carboxylation of Acetyl-CoA
Transamination of amino acids
Carrier of methyl group
Methylation of homocysteine
None of the above
Transamination of amino acids
Thrombin is _____
active enzyme
inactive enzyme
enxyme precursor
proenzyme
eoenzyme
active enzyme
MP, UMP, and TMP all have ________________ as a common precursor.
adenosine aspartate glutamine inosine S-adenosyl methionine
aspartate
Overconsumption of raw eggs results in deficiency of biotin. Raw egg whites contain__
Globulin Avidin Albumin Lecithin Aprotinin
Avidin
Pantetheine derived from the vitamin Pantothrnic acid provides the prosthetic –SH group for__
NAD
Pyridoxamine
Acyl carrier protein
Hydroquinone
None of the above
Acyl carrier protein
Vitamin E functions as an antioxidant and protects polyunsaturated fatty acids from perioxidation. Which…………
Alpha-tocopherol Cholecalciferol 11 cis-retinol alpha-menadiol riboflavinol
Alpha-tocopherol
What is the correct order for clotting mechanism?
Thromboplastin, thrombin, prothrombin, fibrin, fibrinogen
Prothrombin, thromboplastin, thrombin, fibrin, fibrinogen
Fibrin, fibrinogen, thrombin, prothrombin, thromboplastin
Thromboplastin, prothrombin, thrombin, fibrinogen, fibrin
Fibrinogen, fibrin, thromboplastin, prothrombin, thrombin
Thromboplastin, prothrombin, thrombin, fibrinogen, fibrin
