Quiz 3

Question 1

bile pigments are formed in…

Answer 1

the degredation of heme

Question 2

which following enzymes is not involved in the assimilaiton of inorganic nitrogen into an organic molecule

Answer 2

nitrile reductase

arginase

Question 3

which substrate is not involved in the production of urea from NH4 via the urea cycle

Answer 3

malate

Question 4

nitrogen fixation by the dinitrogenase complex produces what gas

Answer 4

produces NH3 and H2 gas

Question 5

siroheme is a heme like prosthetic group used by some enzymes to accomplish the 6 electron reduction of sulfur to nitrogen . it is part of the —- complex

Answer 5

nitrite reductase?, plays a role in the assimilation pathway

Question 6

non essential amino acids

Answer 6

PVT TIM HALL
phenylalanine, valine, threonine
tryptophan , isoleucine , methionine
histidine, arginine, leucine lysine

Question 7

histidine synthesis use which pair of molecules early in the pathway

Answer 7

comes from ribose 5 phosphate. uses purine ring of ATP and gln as source of N

Question 8

an amino acid that does not derive its carbon skeleton at least in part from alpha keto glutarate is

Answer 8

anything except for glutamate, glutamate proline or arginine

Question 9

the enzymatic machinary to fix atmospheric nitrogen into nh4 is

Answer 9

nitrogenase complex. Has 2 Subunits: Dinitrogenase Reductase and dinitrogenase

Question 10

vitamin e functions as an antioxidant and protects poly unsaturated fates from peroxidation which of the following is the active from of vitamin E

Answer 10

alpha tocopherol

Question 11

which of the follwing enzymes is a feeder for the urea cycle

Answer 11

carbomyl phosphate synthetase 1

Question 12

the liquid separated out and placed into a blood tube is

Answer 12

? liquid After clotting = Serum

liquid Before clotting = Plasma

Question 13

the intake of which of the follwing amino acids is need to prevent microtic anemia

Answer 13

?

Question 14

which of the following is the correct order for the steps involved in hemostasis

Answer 14

1. Injury on lining of blood vessel
2. Platelets adhere to cut site
3. platelets secrete things for vasoconstriction
4. Thrombin generated
5. fibrin clot formed
6. clot lysis - wound healing

Question 15

which is released from a damaged tissue to initiate a chain of reactions leading to blood clotting

Answer 15

tissue factor –> thrombin–> fibrinogin –> cross linked

Question 16

which of the following amino acids is used for heme biosynthesis in animals and higher eukaryotes

Answer 16

glycine and succinyl coa

Question 17

which of the following is not an intermeditate in glycolysis or gluconeogeneis in mammalian liver

Answer 17

fructose 2,6 bisphosphate

Question 18

the amino acid — is an intermediate in the biosnthesis of —

Answer 18

glycine , heme

Question 19

which one of the floowing amino acids is directly involved in the purine biosynthetic pathway

Answer 19

aspartate

Question 20

which of the follwoing combination acts a reserve to help maintain the immediate ATP adp ration in highly working muscles

Answer 20

creatine / phosphocreatine

Question 21

Which of the following enzymes is NOT involved in the assimilation of inorganic nitrogen into an organic molecule? 
Arginase 
Glutamate dehydrogenase 
Glutamate synthase 
Glutamine synthetase 
Nitrogenase

Answer 21

Arginase

Question 22

Erythrose 4-phosphate is a precursor of: 
aspartate. 
cysteine. 
phenylalanine. 
serine. 
threonine.

Answer 22

phenylalanine

Question 23

Glutamine synthetase converts ___ to ___ whereas glutamate synthase converts __to___.

Formate; glutamine;
ammonia; glutamate

Asparagine; glutamine;
alpha-ketoglutarate;
glutamate

alpha-ketoglutarate;
glutamine; oxaloacetic acid;
glutamate

alpha-ketoglutarate; glutamine; alpha-ketoglutarate; glutamate

glutamate; glutamine; alpha-ketoglutarate; glutamate

Answer 23

glutamate; glutamine; alpha-ketoglutarate; glutamate

Question 24

Which of the following statements about the fixation of atmospheric nitrogen (N2) into NH3 by living cells is FALSE?

It involves the transfer of 8 electrons per mol of N2.

It occurs in certain microorganisms, but not in humans.
It requires a source of electrons, normally ferredoxin.

It requires one ATP per mol of N2 fixed.

It requires two key protein components, each containing iron.

Answer 24

It requires one ATP per mol of N2 fixed.

Question 25

Which substance is NOT involved in the production of urea from NH4+ via the urea cycle?

Answer 25

``` Aspartate ATP Carbamoyl phosphate Malate Ornithine ```

Question 26

The coenzyme involved in a transaminase reaction is: biotin phosphate. lipoic acid. nicotinamide adenine dinucleotide phosphate (NADP+). pyridoxal phosphate (PLP). thiamine pyrophosphate (TPP).

Answer 26

pyridoxal phosphate (PLP).

Question 27

The human genetic disease phenylketonuria (PKU) can result from: deficiency of protein in the diet. inability to catabolize ketone bodies. inability to convert phenylalanine to tyrosine. inability to synthesize phenylalanine. production of enzymes containing no phenylalanine.

Answer 27

inability to convert phenylalanine to tyrosine.

Question 28

Nonessential amino acids: are amino acids other than those required for protein synthesis. are not utilized in mammalian proteins. are synthesized by plants and bacteria, but not by humans. can be synthesized in humans as well as in bacteria. may be substituted with other amino acids in proteins.

Answer 28

can be synthesized in humans as well as in bacteria.

Question 29

Which of the following is NOT true about the anammox reaction? Anammox converts ammonia to nitrogen Anammox id performed by symbiotic bacteria of leguminous plants Anammox generates the highly reactive molecule hydrazine that is a component of rocket fuel Anammox occurs anaerobically The ultimate electron acceptor in anammox is nitrite

Answer 29

Anammox id performed by symbiotic bacteria of leguminous plants

Question 30

What does von Willebrand factor do? Binds platelets to each other Binds platelets to the sub endothelium Binds platelets to the phospholipid surface Carries factor VII Cleaves factor V

Answer 30

Binds platelets to each other | Binds platelets to the sub endothelium

Question 31

Which of the following is TRUE about gout? Gout is caused by excessive breakdown of pyrimidine nucleotides Gout can be treated by administration of flurouracil Gout is particularly prevalent in patients lacking xanthine oxidase Gout lead to deposition of sodium urate crystals in the joints Eating more liver is an effective way to treat the symptoms of gout

Answer 31

Gout lead to deposition of sodium urate crystals in the joints

Question 32

The ribosyl phosphate moiety needed for the synthesis of orotidylate, inosinate, and guanylate is provided most directly by: 5-phosphoribosyl 1-pyrophosphate. adenosine 5'-phosphate. guanosine 5'-phosphate. ribose 5-phosphate. ribulose 5-phosphate.

Answer 32

5-phosphoribosyl 1-pyrophosphate.

Question 33

Pyridoxal phosphate is required as a co-factor for which of the following? Carboxylation of Acetyl-CoA Transamination of amino acids Carrier of methyl group Methylation of homocysteine None of the above

Answer 33

Transamination of amino acids

Question 34

Thrombin is _____ active enzyme inactive enzyme enxyme precursor proenzyme eoenzyme

Answer 34

active enzyme

Question 35

MP, UMP, and TMP all have ________________ as a common precursor. ``` adenosine aspartate glutamine inosine S-adenosyl methionine ```

Answer 35

aspartate

Question 36

Overconsumption of raw eggs results in deficiency of biotin. Raw egg whites contain__ ``` Globulin Avidin Albumin Lecithin Aprotinin ```

Answer 36

Avidin

Question 37

Pantetheine derived from the vitamin Pantothrnic acid provides the prosthetic –SH group for__ NAD Pyridoxamine Acyl carrier protein Hydroquinone None of the above

Answer 37

Acyl carrier protein

Question 38

Vitamin E functions as an antioxidant and protects polyunsaturated fatty acids from perioxidation. Which………… ``` Alpha-tocopherol Cholecalciferol 11 cis-retinol alpha-menadiol riboflavinol ```

Answer 38

Alpha-tocopherol

Question 39

What is the correct order for clotting mechanism? Thromboplastin, thrombin, prothrombin, fibrin, fibrinogen Prothrombin, thromboplastin, thrombin, fibrin, fibrinogen Fibrin, fibrinogen, thrombin, prothrombin, thromboplastin Thromboplastin, prothrombin, thrombin, fibrinogen, fibrin Fibrinogen, fibrin, thromboplastin, prothrombin, thrombin

Answer 39

Thromboplastin, prothrombin, thrombin, fibrinogen, fibrin