Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Meharry Biochem > Blood > Flashcards

Blood Flashcards

1
Q

what 2 things are blood composed of

A

cells and liquid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what kind of cells are found in blood

A

rbc (erythorcytes), WBC( Leukocytes), platlets (thombocytes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

the liquid in blood is also known as

A

plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

can you donate serum

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is the difference between plasma and serum

A 
plasma = blood - cells before clotting 
serum = blood - cells after clotting
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

if you put anti coag in a tube with blood will you get blood or plasma

A

plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

when clot formation occurs do you have plasma or serum

A

serum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

before clot formation occurs do you have plasma or serum

A

plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

the packed cell volume is also known as

A

hematocrit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

hematocrit refers to the %

A

% of total red blood cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what are the normal hematocrit values for men and women

A

men - 38.8-50

women - 34.9 -44.5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

if you live in high altitude will you have higher or lower levels of hematocrit

A

higher levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

why do you have higher levels of hematocrit at high altitude

A

since there is less 02 in the air , the body compensates by making more RBC’s which in turn elevates hematocrit levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

can you donate serum

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is the intrinsic pathway

A

all clotting factors within the blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

is clotting faster in the intrinsic or extrinsic pathway

A

extrinsic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is the extrinsic pathway

A

initiating factor is outside the blood vessels - tissue factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

how long does the extrinsic pathway take

A

seconds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what kind of molecule is the tissue factor

A

protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

tissue damage exposes blood to

A

tissue factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

coagulation cascade refers to a series of enzymatic reactions that converts

A

fibrinogen to fibrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

fibrin becomes ____ and forms ____

A

cross linked , clot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

if fibrinogen present in plasma or serum

A

in plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

is fibrinogen found in serum

A

no !

25
Q

what protein is present only in plasma and not in serum

A

fibrinogen

26
Q

what is the major site where the intrinsic and extrinsic pathway converge

A

xA

27
Q

is the tissue factor found in the intrinsic or extrinsic pathway

A

extrinsic

28
Q

describe the pathway from the Xa

A

Xa converts prothrombin to thrombin
thrombin converts fibrinogen to fibrin monomer
fibrin monomer –> finbrin polymer (clot)

29
Q

what does fibrinolysis refer to

A

breakdown of a clot

30
Q

what is the enzyme that breaks down clots

A

plasmin

31
Q

what is the responsible for converting plasmingen to plasmin ?

A

plasiminogen activators

32
Q

list the steps of clot break down

A

plaminogen activator –> plasminogen –> plamin –> lysis of fibrin –> clot breaks

33
Q

which chemical is is the most effective to remove a blockage of a coronary artery to a blood clot

A

plasminogen activator because it enhaves fibrinolysis and dissolves the thrombus (fibrin clot) in blood vessel

34
Q

which vitamin is needed to synthesize clotting factors

A

vitamin K

35
Q

if someone has a vitamin k deficiency what can occur

A

people will bleed easily which could lead to hemorage

36
Q

what the function of warfarin

A

it is a blood thinner because it interferes with vitamin k

37
Q

would ginving someone warfarnin learn to thrombosis or no

A

no it would prevent it

38
Q

what 2 things work togetner to form clot .

A

vitamin k and calcium

39
Q

would someone with low calcium levels be at risk of thrombosis or hemmoarge

A

hemorage

40
Q

what is venus thrombosis

A

blockage of blood return and associated inflammation causes swelling , pain
if clot is disloged it could travel to the heart

41
Q

what is arterial thrombosis

A

clot prevents inflow of blood causing tissue death

42
Q

is myocardial infarction an example of venous thrombosis or arterial thrombosis

A

arterial

43
Q

What is thrombocytopenia

A

low platelet count ( may cause bleeding )

44
Q

what is thrombocytosis

A

high platlet count

45
Q

is thrombocytopenia or thrombocytosis more likely to lead to a thrombosis

A

thrombocytosis

46
Q

each hemoglobin molecule has how many heme and how many globin

A

4 and 4

47
Q

what 2 proteins make up hemoglobin

A

heme and globin

48
Q

what 2 kind of subunits make up globin

A

2 alpha and 2 beta

49
Q

each globin contain how many heme and fe

A

1 heme and 1 fe

50
Q

describe what makes up heme

A

iron containing porphyrin

metaloporphyrin

51
Q

how many nitrogen atoms and iron

A

4 Nitrogen and 1 IRON

52
Q

a patient has a blood clot what would you give them

A

thrombolytic drugs ( plasminogen activators)

53
Q

what would you give someone to prevent a blood clot

A

anticoagulants - heparin or warfarin

54
Q

what are the hemoglobin derivatives

A

oxyhemoglobin, deoxyhemoglobin, carbaminohemoglobin

55
Q

what is the primary polycythemia

A

blood cancer, high hematocrit value

56
Q

what is secondary polycythemia

A

physiologic condition resulting from deficient 02 supply to the tissues. The body attempts to compensate by making more hemoglobin and erythrocytes. basically ther is high hematocrit level

57
Q

living at high altitude could lead to what condition”S”

A

secondary polycythemia AND high hematocrit

58
Q

give 3 examples of acquired bleeding disorders

A

liver disease
vitamin K
Disseminated intravascular coagulation and fibrinolysis

Meharry Biochem (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions