Blood Flashcards by Adrienne carter

what 2 things are blood composed of

cells and liquid

How well did you know this?

Not at all

Perfectly

what kind of cells are found in blood

rbc (erythorcytes), WBC( Leukocytes), platlets (thombocytes)

How well did you know this?

Not at all

Perfectly

the liquid in blood is also known as

plasma

How well did you know this?

Not at all

Perfectly

can you donate serum

How well did you know this?

Not at all

Perfectly

what is the difference between plasma and serum

plasma = blood - cells before clotting 
serum = blood - cells after clotting

How well did you know this?

Not at all

Perfectly

if you put anti coag in a tube with blood will you get blood or plasma

plasma

How well did you know this?

Not at all

Perfectly

when clot formation occurs do you have plasma or serum

serum

How well did you know this?

Not at all

Perfectly

before clot formation occurs do you have plasma or serum

plasma

How well did you know this?

Not at all

Perfectly

the packed cell volume is also known as

hematocrit

How well did you know this?

Not at all

Perfectly

hematocrit refers to the %

% of total red blood cells

How well did you know this?

Not at all

Perfectly

what are the normal hematocrit values for men and women

men - 38.8-50

women - 34.9 -44.5

How well did you know this?

Not at all

Perfectly

if you live in high altitude will you have higher or lower levels of hematocrit

higher levels

How well did you know this?

Not at all

Perfectly

why do you have higher levels of hematocrit at high altitude

since there is less 02 in the air , the body compensates by making more RBC’s which in turn elevates hematocrit levels

How well did you know this?

Not at all

Perfectly

can you donate serum

How well did you know this?

Not at all

Perfectly

what is the intrinsic pathway

all clotting factors within the blood vessels

How well did you know this?

Not at all

Perfectly

is clotting faster in the intrinsic or extrinsic pathway

extrinsic

How well did you know this?

Not at all

Perfectly

what is the extrinsic pathway

initiating factor is outside the blood vessels - tissue factor

How well did you know this?

Not at all

Perfectly

how long does the extrinsic pathway take

seconds

How well did you know this?

Not at all

Perfectly

what kind of molecule is the tissue factor

protein

How well did you know this?

Not at all

Perfectly

tissue damage exposes blood to

tissue factor

How well did you know this?

Not at all

Perfectly

coagulation cascade refers to a series of enzymatic reactions that converts

fibrinogen to fibrin

How well did you know this?

Not at all

Perfectly

fibrin becomes ____ and forms ____

cross linked , clot

How well did you know this?

Not at all

Perfectly

if fibrinogen present in plasma or serum

in plasma

How well did you know this?

Not at all

Perfectly

is fibrinogen found in serum

no !

what protein is present only in plasma and not in serum

fibrinogen

what is the major site where the intrinsic and extrinsic pathway converge

is the tissue factor found in the intrinsic or extrinsic pathway

extrinsic

describe the pathway from the Xa

Xa converts prothrombin to thrombin thrombin converts fibrinogen to fibrin monomer fibrin monomer --> finbrin polymer (clot)

what does fibrinolysis refer to

breakdown of a clot

what is the enzyme that breaks down clots

plasmin

what is the responsible for converting plasmingen to plasmin ?

plasiminogen activators

list the steps of clot break down

plaminogen activator --> plasminogen --> plamin --> lysis of fibrin --> clot breaks

which chemical is is the most effective to remove a blockage of a coronary artery to a blood clot

plasminogen activator because it enhaves fibrinolysis and dissolves the thrombus (fibrin clot) in blood vessel

which vitamin is needed to synthesize clotting factors

vitamin K

if someone has a vitamin k deficiency what can occur

people will bleed easily which could lead to hemorage

what the function of warfarin

it is a blood thinner because it interferes with vitamin k

would ginving someone warfarnin learn to thrombosis or no

no it would prevent it

what 2 things work togetner to form clot .

vitamin k and calcium

would someone with low calcium levels be at risk of thrombosis or hemmoarge

hemorage

what is venus thrombosis

blockage of blood return and associated inflammation causes swelling , pain if clot is disloged it could travel to the heart

what is arterial thrombosis

clot prevents inflow of blood causing tissue death

is myocardial infarction an example of venous thrombosis or arterial thrombosis

arterial

What is thrombocytopenia

low platelet count ( may cause bleeding )

what is thrombocytosis

high platlet count

is thrombocytopenia or thrombocytosis more likely to lead to a thrombosis

thrombocytosis

each hemoglobin molecule has how many heme and how many globin

4 and 4

what 2 proteins make up hemoglobin

heme and globin

what 2 kind of subunits make up globin

2 alpha and 2 beta

each globin contain how many heme and fe

1 heme and 1 fe

describe what makes up heme

iron containing porphyrin | metaloporphyrin

how many nitrogen atoms and iron

4 Nitrogen and 1 IRON

a patient has a blood clot what would you give them

thrombolytic drugs ( plasminogen activators)

what would you give someone to prevent a blood clot

anticoagulants - heparin or warfarin

what are the hemoglobin derivatives

oxyhemoglobin, deoxyhemoglobin, carbaminohemoglobin

what is the primary polycythemia

blood cancer, high hematocrit value

what is secondary polycythemia

physiologic condition resulting from deficient 02 supply to the tissues. The body attempts to compensate by making more hemoglobin and erythrocytes. basically ther is high hematocrit level

living at high altitude could lead to what condition"S"

secondary polycythemia AND high hematocrit

give 3 examples of acquired bleeding disorders

liver disease vitamin K Disseminated intravascular coagulation and fibrinolysis