Questions x Flashcards

1
Q

Meissners plexus

A

Submuscosa plexus

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2
Q

Aurbachs plexus

A

Myenteric plexus

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3
Q

Murphys sign

A

Acute cholecystitis

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4
Q

Gentamicin

A

Aminoglycoside inhibiting 30s unit of ribosomes

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5
Q

Quiet inspiration

A

Contraction of diaphragm and external IC muscles

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6
Q

B1 agonists

A

Positive inotropy

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7
Q

Cyclizine

A

Anrihistamine

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8
Q

Resp control centre for basic rhythm of resp

A

Doral respiratory group

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9
Q

Expiratory centre that controls active expiration

A

Ventral respiratory group

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10
Q

Hb CAg

A

Hep B core antigen - If youve had it silly bobs

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11
Q

Vaccinated against Hep B

A

HbSAg neg, Anti-HbS positive,

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12
Q

Excess PTH

A

Hypercalcaemia

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13
Q

ACID EGG-T - reactions and mediators

A
1 - Anaphylactic 
2 - Cytotoxic 
3 - Immune complex 
4 - Delayed 
IgE, IgG, IgG and T
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14
Q

TB granulomas

A

Caseating

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15
Q

Sarcoidosis granulomas

A

Non-caseating

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16
Q
A

T

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17
Q

Can cause TB

A

TNF-alpha inhibitors

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18
Q

80-year-old male patient presenting to his GP with symptoms of pneumonia. They have new onset confusion, urea = 6.2, RR = 33, BP = 80/60. They have no known penicillin allergy.

A

IV Co-amoxiclav + PO Doxycycline

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19
Q

From cold to cough and struggling for breath, intercostal recession, audible wheeze and crackles

A

Bronchiolitis

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20
Q

Club cells in resp

A

Secrete glycosaminoglycans which protect epithelial lining of bronchioles

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21
Q

Found on cell membrane of macrophages

A

MHC II

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22
Q

Negative enthalpy and positive entropy

A

Exothermic, exergonic and spontaneous

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23
Q

Endergonic

A

Cannot happen spontaneously, energy is absorbed

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24
Q

exergonic

A

Releases energy

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25
Q

State of potassium channels in hyperpolarisation

A

Open also… dk why

26
Q

Down’s syndrome most appropriate detection method

A

Array competitive genomic hybridisation

27
Q

Sarcomas

A

Malignant connective tissue tumour

28
Q

Bifurcation of the trachea occurs at

A

T4/5

29
Q

Male nipple level

A

T4

30
Q

Necrosis where basic outline of cells is preserved

A

Coagulative

31
Q

Peyer’s patches

A

Aggregations of lymphoid tissue found in the ileum

32
Q

Emphysema and lung compliance

A

Increases lung compliance

33
Q

Cardiac syncitium

A

Individual cardiomyocytes connected by intercalated discs

34
Q

Hypersensitivity type of goodpasture’s

A

II

35
Q

PTH

A

Increase blood calcium and increase phosphate excretion

36
Q

Chronic bronchitis

A

Obstructive

37
Q

mean systemic filling pressure

A

pressure that would be present in circulation if the heart was removed

38
Q

Poisuelle’s laww

A

States that the resistance to blood flow is directly proportional to length of blood vessel and viscosity of blood

39
Q

Best representation of afterload

A

MAP

40
Q

Good indication of preload

A

EDV

41
Q

How many cusps does the aortic valve usually have

A

3

42
Q

Lung compliance

A

Change in lung volume per unit change in pressure

43
Q

Chronic bronchitis

A

Chronic exposure to noxious particles such as smoking or air pollutants causes mucous gland hyperplasia and oversecretion of mucus

44
Q

Coronary blood flow is highest during

A

Diastole

45
Q

Chronic alcohol excess and jaundice

A

Hepatic cause, impaired uptake of bilirubin by the hepatocytes

46
Q

Adrenoceptors in the heart muscle

A

Beta-1

47
Q

Adrenoceptors in the blood vessels

A

Alpha-1

48
Q

Pulmonary shunt

A

Alveoli are perfused but ventilation is impaired

49
Q

Dark urine and pale stools

A

Cholestasis

50
Q

Phase 1 drug metabolism

A

Drug made mor epolar, adds groups

51
Q

Phase 2 drug metabolism

A

Adds an endogenous compound, increasing polarity - conjugation

52
Q

Phase 1 drug metabolism reactions

A

Oxidation, reduction and hydrolysis

53
Q

Negative predictive value

A

Number of true negatives divided by total negatives

54
Q

Positive predictive value

A

Number of true positives divided by the number of positives

55
Q

Group A strep haemolysis

A

Beta haemolysis

56
Q

Strep pneumoniae haemolysis

A

Alpha

57
Q

Staph epidermis haemolysis

A

Gamma

58
Q

BRCA1 and 2

A

Breast cancer

59
Q

RAS gene mutation

A

Colon/lung/pancreatic

60
Q

BRAF gene mutation

A

Colonic cancer

61
Q

Is clarithromycin one of the 4 Cs?

A

No you sillly fresher