also these Flashcards

1
Q

How does omeprazole work?

A

inhibits H+/K+-ATPase, which is found in parietal cells

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2
Q

The Bainbridge reflex

A

increase in heart rate mediated via atrial stretch receptors that occurs following a rapid infusion of blood

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3
Q

rheumatic fever acts via

A

molecular mimicry

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4
Q

molecular mimicry

A

a cross-reaction between the host cell and microbial agents which leads to autoimmunity

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5
Q

Bystander activation

A

cytokines released by antigen-presenting cells don’t only interact with the intended T-cell but end up activating “bystander” T-cells, leading to autoimmune destruction.

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6
Q

exposure to cryptic antigens

A

self-epitopes, which are usually removed and destroyed via apoptosis by T-reg cells are termed cryptic because they are not detected. Therefore, auto-reactive T-cells are not destroyed and join the periphery, causing autoimmunity.

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7
Q

Super-antigens

A

a class of antigens that cause excessive activation of T-cells, leading to autoimmune destruction of tissues.

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8
Q

viral persistence

A

viral infections where the virus is not cleared completely but remains in specific cells of infected individuals.

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9
Q

action of atrial natriuretic peptide

A

angiotensin II antagonist

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10
Q

elevated in post hepatic jaundice

A

Alkaline phosphatase

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11
Q

Reduce effectiveness of gastric mucosal barrier

A

salicylates such as apririn

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12
Q

colipase

A

prevents inhibitory effect of bile salts on lipase-catalysed hydrolysis of triglyceride fats

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13
Q

site of bile acid reabsorption

A

terminal ileum

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14
Q

reabsorbed bile acids enter

A

enterohepatic circulation to the liver

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15
Q

isoap

A

Ipratropium, salbutamol, oxygen, amoxicillin and prednisolone

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16
Q

oshitman

A

Oxygen, salbutamol, (hi prednisolone), Ipratropium bromide and theophylline. magnesium and anaesthetist

17
Q

Causes of acute pancreatitis

A

I GET SMASHED

18
Q

I GET SMASHED

A

Idiopathic, gallstones, ethanol, trauma, steroids, mumps, autoimmune, scorpion hyperlipidaemia/hypercalcaemia, ERCP, drugs

19
Q

6 Ps of pale limb ischaemia

A

Pallor, pulselessness, pain, paraesthesia, paralysed, perishingly cold

20
Q

ABCDEFGHI of liver disease

A

Autoimmune, HepB, HepC, Drugs, Ethanol, Fatty liver disease, Growth, Haemodynamic, Infiltration (wilson’s and haemochromatosis)

21
Q

Increased in alcoholic liver disease

A

AST - alcohol gets you wASTed