GI hormones Flashcards
Gastrin produced by
G cells in stomach
Gastrin function (3)
Stimulates parietal cells to produce HCl and release of pepsinogen from chief cells / stimulates bile and pancreatic enzyme secretion
Triggers of gastrin release
Anticipation of eating / distension of stomach / pH of stomach increasing
Production of gastrin slowed by
Somatostatin
Somatostatin secreted by
D cells
Zollinger-Ellison syndrome
Gastrin-secreting tumours
Stimulates CCK
Presence of fatty acids in chyme
Functions of CCK
Stimulates gallbladder contraction and release of pancreatic enzymes,
Inhibition of CCK
Somatostatin, trypsin, pancreatic polypeptide
Secretin released in intestinal lumen in response to
Low pH
Secretin action
Bicarbonate rich solution release
Release of CCK triggered by
Fat in chyme
Pepsinogen released from
Chief cells
Trigger of somatostatin release
Low pH
Motilin
Stimulates migrating motor complex