(Q4) Embalming Chemistry Concepts Flashcards

1
Q

Primary Disinfection

A
  • Disinfection done before the embalming procedure begins
  • May consist of cleaning the deceased; cleaning the eyes, mouth, or orifices
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2
Q

Concurrent Disinfection

A
  • Disinfection during the embalming operation
  • Disinfection that occurs during injection and cavity embalming
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3
Q

Terminal Disinfection

A
  • Disinfection after the embalming operation to protect the environment
  • May consist of cleaning the deceased, cleaning the instruments and the table
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4
Q

The Three Primary Preservative Agents in Embalming Chemicals

A
  • Aldehydes
  • Alcohols
  • Phenols
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5
Q

Five Common Characteristics of All Embalming Chemicals

A
  • Inactivate the chemical groups of proteins or amino acids
  • Inhibit further decomposition
  • Inactivate enzymes (both of the tissues and microorganisms)
  • Kill microorganisms
  • Destroy or mask odors and eliminate their further production
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6
Q

Inactivate the chemical groups of proteins or amino acids

A
  • The nitrogen in proteins are sites of decomposition
  • The chemicals react with the nitrogen to change the structure of the protein (coagulation)
  • Coagulation decreases the likelihood that the protein will hydrolyze
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7
Q

Inhibit further decomposition

A
  • Chemicals only slow down decomposition
  • therefore, embalming as soon as possible is best
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8
Q

Inactivate Enzymes

A
  • Enzymes are important catalysts of hydrolysis
  • Inactivating the enzymes will slow down decomposition
  • enzymes are similar to proteins, so preservative chemicals will inactivate enzymes similar to tissue proteins
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9
Q

Kills Microorganisms

A
  • The chemical change that proteins undergo during embalming deprives bacteria of their primary source of nutrition
  • Preservative chemicals denature the structural proteins of the bacteria themselves
  • The same chemical actions that cause fixation of the tissues of the remains will also produce fixation of the bacterial invaders
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10
Q

Destroys/Masks odors and eliminates their further production

A
  • The odors associated with decomposition are principally due to the formation of amines
  • The decomposition of structural proteins produces amines such as putrescine, cadaverine, indole, skatole
  • Decomposition of sulfur-containing proteins also contributes to odors
  • Protein chemicals react with the nitrogen to effectively neutralize the odor
  • Preservative chemicals react with the sources of decomposition (putrefactive bacteria and autolytic enzyme) to eliminate the further production of odors
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11
Q

Reactions of Formaldehyde and Water

A
  • HCHO and water produce methylene glycol
  • The proteins are fixed due to the donation of a methylene group (methylene bridge)
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12
Q

Formaldehyde in aqueous solution is:

A
  • formalin
  • 37% HCHO by weight
  • 40% by volume
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13
Q

How are the proteins fixed?

A
  • the donation of a methylene group (-CH2): methyl/methylene bridge
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14
Q

Reactions of Formaldehyde with Methanol

A
  • Methanol prevents the polymerization of formaldehyde
  • Helps extend shelf life
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15
Q

Reactions of Formaldehyde with Proteins

A
  • Main chemical action of HCHO in embalming is the coagulation of protein
  • This is brought about by the cross-linking of the peptide bonds of adjacent proteins
  • The changes in protein only happen in normal amounts of water; excess water could ever the embalming process by hydrolyzing the cross-links
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16
Q

The changes in protein brought about by formaldehyde are

A
  • Viscosity is increased
  • Tissues become firmer
  • Resistance to digestive enzymes is increased
  • Hydrolysis and water solubility are decreased
17
Q

Reactions of Formaldehyde with Amino Acids

A
  • Formaldehyde will react with amino acids similarly to protein, because amino acids are the building blocks of proteins
18
Q

Reactions of Formaldehyde with Strong Bases

A
  • Formaldehyde is destroyed in strong bases
19
Q

What are two of the strong bases produced by decomposition?

A

Amines and ammonia

20
Q

What implications will amines and ammonia have for embalming?

A

Because Amines and ammonia are strong bases formed by decomposition, and formaldehyde is destroyed by strong bases
- These strong bases may call for a higher formaldehyde demand to combat them

21
Q

What pH is formaldehyde considered?

A

a weak acid

22
Q

Reactions of Formaldehyde with Hemoglobin

A
  • Formaldehyde and hemoglobin produce methemoglobin
  • Methemoglobin can turn the body black in 2-3 days
  • Preventing the over-formation of methemoglobin is another reason for drainage
23
Q

Preservative Demand/Formaldehyde Demand

A
  • The amount of formaldehyde/preservative necessary to overcome any nitrogen residue and cause the body proteins to become coagulated
  • The total amount of formaldehyde with which protein will combine to be completely preserved
  • The greater the decomposition, the greater the formaldehyde demand
24
Q

Walling-Off Action

A
  • When the concentrated solution seals and sear the capillaries in the tissues preventing distribution and diffusion of the fluid
  • causes “shell embalming”
  • Caused by too concentrated solutions of formaldehyde or too high rate of flow
25
Q

What is “shell embalming”

A

When the embalming solution follows the direct connections between the arterioles and venules and only the surface receives embalming solution, giving a false impression to the embalmier

26
Q

Distribution

A
  • The movement of arterial solution from the point of injection throughout the arterial system to the arteries.
  • Solution moves from carotid (or other injection vessels) to the rest of the arteries
27
Q

Diffusion

A
  • The movement of arterial solution from inside the vascular system (intravascular) through the walls of the capillaries to the tissues (extravascular
  • (after it gets to the other arteries) Solution moves into the capillaries where it disperses to the tissues