Pyruvate Metabolism Flashcards

1
Q

Pyruvate to lactic acid cofactor ?

A

Vitamin B3 Niacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Pyruvate to alanine cofactor?

A

Vitamin B6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Pyruvate to Acetyl Coa Cofactors?

A

The Lovely Coenzyme For Needs

Thiamine phosphate (B1)
Lipoamide
Coenzyme A (B5)
FAD (RIBOFLAVIN)
NADH (NIACIN)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Name the 3 complex of Pyruvate Dehydrogenase.?

A

Pyruvate Dehydrogenase
Dihydrolipyl Transacetylase
Dihydrolipyl Dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Does phosphorylated PDH an active or inactive enzyme ?

A

Inactive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the cause of lactic acidosis?

A

Increase in Cori cycle and more lactate.
Decrease in Pyruvate Dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the diseases associatied with B1 Thiamine deficiency.?

A

Werkinke korkoff (Alcoholics)
Dry BER1 BER1 (peripheral nerves)
WET BERI BERI (heart capillaries)
INFANTILE BERI BERI (quiet cry, tachycardia) (B1 Deficient in MOM)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What the enzymes that requires B1 as a cofactor ?

A

Pyruvate Dehydrogenase
Alpha keto glutarate Dehydrogenase
Branched keto acid Dehydrogenase
Transketolase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What aree the symptoms of Riboflavin (B2)deficiency ?

2C of B2

A

Chelosis
Corneal Vascularisation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What the enzymes that requires Riboflavin as a cofactor ?

A

Succinate Dehydrogenase
Acyl CoA Dehydrogenase
NADH Dehydrogenase
Di hydrolipoyl Dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the symptoms of NIACIN (B3) Deficiency ? (PHDDD)

A

Pellegra
HARTNUP
CARCINOID SYNDROME
DIARRHEA
DEMENTIA
DERMATITS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly