ETC CYCLE

Question 1

What are the two carriers of etc ?

Answer 1

Co-q and cytochrome C

Question 2

Which complex in etc cycle transport NADH and FADH2 respectively ?

Answer 2

COMPLEX 1 ( NADH DEHYDROGENASE)
COMPLEX 2 (SUCCINATE DEHYDROGENASE)

Question 3

What are the components of cytochrome 3 (CYTOCHROME C REDUCTASE)

Answer 3

B and C1

Question 4

What are the components of cytochrome 4? ( CYTOCHROME C oxidase)

Answer 4

A and A 3

Question 5

How many ATP does 1 NADH and 1 FADH2 produce?

Answer 5

NADH = 2.5ATP
FADH2 = 1.5ATP

Question 6

What is the cause of HYPOXIA (LACTIC ACIDOSIS) in ETC?

Answer 6

Decreased Oxyggen
No final electron acceptor
Decreased ATP production
Increased Lactic acid product

Question 7

What is the molecule formed when Coenzyme -Q passes electron to oxygen ?

Answer 7

ROS

Question 8

What complex does Barbiturates affect in ETC?

Answer 8

COMPLEX 1 INHIBITON
Accumulates NADH

Question 9

What does Rotenone (insecticide) inhibit in etc ?

Answer 9

Complex 1 (only NADH) NOT FADH2

Question 10

What drug inhibits only complex 3?

Answer 10

Antimycin A
Prevents electron transport from complex 1 and FADH2 TO cytochrome C

Question 11

Inhibitors of complex 4

Answer 11

CYANIDE AND CO

Question 12

Oxidative phosphorylation inhibitors of ETC?

Answer 12

ATRACTYLOSIDE
OLIGOMYCIN

Question 13

2 drug examples of uncouplers?

Answer 13

ASPRIN
2,4 dinitro-phenol